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Found 64,783 clinical trials
Y Yen-lin Chen

Applying Shear Wave Elastography for Adjunct Steroid on Tuberculous Lymphadenitis

To prospectively collect the radiologic data from the initial phase till the post-treatment phase of tuberculous lymphadenitis. To prospectively investigate the benefits of corticosteroid on reduction of paradoxical upgrading reaction in patients with tuberculous lymphadenitis based on the results of shear wave elastography. To investigate the potential biomarker of host …

18 years of age All Phase N/A
E ELIZABETH NALINTYA, MPH

Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia

This will be a randomized controlled trial of asymptomatic (Cryptococcal Antigen test)CrAg positive persons in Uganda. Patients will be randomized to receive preemptive treatment with 1 dose of liposomal amphotericin (10mg/kg) in addition to standard of care fluconazole therapy. How the enhanced antifungal therapy prevents progression to meningitis in the …

15 years of age All Phase 2/3

Dose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors

This is a Phase1 study to assess the safety, PK, PD and efficacy of HM97662, EZH1/2 dual inhibitor, in solid tumors. The study will be conducted in Dose-Escalation and Dose-Expansion parts. Dose-Escalation Part is planned with a 3+3 Dose-Escalation design and is to establish the MTD or RD for Dose-Expansion …

18 years of age All Phase 1
V Veronica Formanek, BS

Nasal Obstruction and Olfactory Losses

About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to …

18 - 70 years of age All Phase N/A
Z Zhenzhen Liu, PhD

Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation

To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia

18 - 14 years of age All Phase N/A
S Sonjia Kenya, EdD

Integrated Navigation Services for Treatment Adherence, Counseling, and Research

The goal of this research is to determine whether a Community Health Worker (CHW) intervention including a mobile telehealth (M-Health) component can help achieve long term viral suppression among Black people with poorly controlled HIV.

18 years of age All Phase N/A

A Study of QY101 Ointment in Subjects With Plaque Psoriasis

The goal of this clinical trial is to evaluate the effectiveness of QY101 ointment in adult patients with plaque psoriasis (2-20% BSA).

18 - 75 years of age All Phase 2
Y Yunfei Chen, MD

Avatrombopag for Chemotherapy-induced Thrombocytopenia

To evaluate the efficacy and safety of Avatrombopag to treat chemotherapy-induced thrombocytopenia in solid tumors

18 years of age All Phase 2
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

Background Brain activity produces magnetic fields. These fields can be measured outside the head. Existing technology, called MEG, measures these fields. Researchers are testing a new type of magnetic field sensor called OPM. They hope it can help pinpoint with very high accuracy where brain activity is generated. Objective To …

18 - 65 years of age All Phase N/A
E Elizabeth K Turner

Conservative Management for PAS Pilot

Conservative in situ management is a promising alternative treatment to hysterectomy for patients with placenta accreta spectrum and may be safer and preferable for some patients. This study will assess feasibility of a future randomized clinical trial comparing these treatments and provide novel data to inform shared decision-making and cost-effective …

18 - 99 years of age Female Phase N/A

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