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Found 1,873 clinical trials
X Xiaohua Zhu

A Hierarchical Multi-modal AI Framework for Pathological and Genetic Subtyping of Lung Cancer Based on PET/CT Imaging

PET/CT imaging and clinical information (age, gender, smoking history, family history of cancer, history of present illness, and several tumor biomarkers, etc.) were used to establish a hierarchical multi-modal AI framework for pathological and genetic subtyping of lung cancer

18 years of age All Phase N/A
W Wei Ping

Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection

This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection. Patients who can undergo pulmonary resection and meet the eligibility criteria will be studied during routine clinical care; the research will not assign the surgical procedure or add a …

18 years of age All Phase N/A

TROP2 NMR Concordance Study

This is a two-stage, multi-center study to compare concordance of Local solution and Mixed solution with a Reference solution in testing TROP2 NMR in untreated advanced NSCLC patients, as well as clinical application and robustness in real world labs. TROP2 NMR testing by QCS is composed of three main components: …

18 years of age All Phase N/A
F Fan Yang, MD

Clinical Study of a New Treatment Model for Elderly Lung Cancer Patients

This multicenter prospective clinical study focuses on elderly patients with lung cancer. We will build a standardized clinical registry database, develop perioperative risk stratification and surgical early-warning models, optimize individualized surgical regimens, construct multidisciplinary perioperative comprehensive therapy, integrated Chinese-Western medicine full-cycle management and personalized postoperative rehabilitation systems, so as to …

65 years of age All Phase N/A
L Lydia Taylor

DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction Solution

This study is a multi-centre prospective observational cohort study recruiting patients with 5-30mm solid and part-solid pulmonary nodules that have been detected on CT chest scans performed as part of routine practice. The aim is to determine whether physician decision making with the AI-based LCP tool, generates clinical and health-economic …

35 years of age All Phase N/A
Y Yi-Bin Hua, MD

Intraoperative Blood Pressure Management and Dexamethasone in Lung Cancer Surgery

Surgery is the front-line therapy for non-small cell lung cancer (NSCLC) but postoperative complications remains high and patients' long-term outcome is still challenging. In addition to surgery, anesthetic management particularly intraoperative blood pressure management and use of dexamethasone may affect patients' early and long-term outcomes after surgery for NSCLC. This …

50 - 90 years of age All Phase N/A

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

The purpose of this study is to assess the safety and efficacy of multiple study interventions including novel-novel combinations or novel agents in combination with standard therapy for the treatment of metastatic NSCLC.

18 years of age All Phase 1/2
N Nong Yang, Doctor

Chemotherapy With or Without Immune Checkpoint Inhibitors for Lung Cancer

Although several clinical trials provide evidence for efficacy benefit for Checkpoint Inhibitors plus chemotherapy for lung cancer. However, there was rare evidence for clinical evidence in Hunan province.

18 years of age All Phase N/A
F Feng-Ming (Spring) KONG, Professor

RAPART in Locally Advanced Non-small Cell Lung Cancer Patients

This is a Phase II/III randomized clinical trial of Radiosensitivity-Assisted Personalized Adaptive Radiotherapy Technology (RAPART) in locally advanced non-small cell lung cancer patients. The main objective is to test the overall improvement of overall survival (OS), progression free survival (PFS), and local progression free survival (LPFS) of unresectable stage III …

18 years of age All Phase N/A
E Elyse Park, PhD

Health Opportunities and Promoters of Equitable Screening for Lung Cancer

The goal of this clinical trial is to promote lung cancer screening (LCS) uptake among Hispanic current and former smokers. The main questions it aims to answer are: What barriers do current and former Hispanic smokers face in the identification and documentation of their smoking status? How can digital delivery …

50 - 80 years of age All Phase N/A

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