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Found 296 clinical trials

Different Models of Tracheal Catheters Are Used for Female Thyroid Glands

Objective:Compare whether the use of tracheal catheters of models 6.0 and 6.5 causes less sore throat in women after thyroid surgery compared with the traditional use of model 7.0 tracheal catheters.Methods:Investigators enrolled 180 female patients with American Society of Anesthesiologists (ASA) physical status I and III, aged 18-65 years, and …

18 - 65 years of age Female Phase N/A
S Site Public Contact

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

This phase III trial compares the effect of cabozantinib versus combination dabrafenib and trametinib for the treatment of patients with differentiated thyroid cancer that does not respond to treatment (refractory) and which expresses a BRAF V600E mutation. Cabozantinib is in a class of medications called receptor tyrosine kinase inhibitors. It …

18 years of age All Phase 3
h huifang zhou, Doctor

A Study of GenSci098 in Subjects With Active Thyroid Eye Disease

To evaluate the safety and tolerability of single and multiple ascending subcutaneous doses of GenSci098 in patients with thyroid eye disease (TED)

18 - 75 years of age All Phase 1
T Theodore Laetsch

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve a complete response to RAI therapy, …

2 - 25 years of age All Phase 2
E Ethics Committee

Open-Label Extension Study of MHB018A in Subjects With Thyroid Eye Disease

This is a multicenter, open-label extension (OLE) study of MHB018A in subjects with moderate-to-severe TED.

18 - 75 years of age All Phase 3
y yan li, B.S

Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules

The purpose of this observational research is to evaluate and compare the health-related quality of life and emotional well-being of patients with thyroid nodules before and after treatment. This is a data collection study by allowing investigators to access information generated before and after treatment.

18 - 70 years of age All Phase N/A
J Jennifer H Kuo, MD MS

RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study

The purpose of this observational research is to evaluate and compare clinical outcomes after treatment for symptomatic benign multinodular goiter (MNG) patients. This is a data collection study in which we ask participants to give access to information generated before and after treatment of their condition.

18 years of age All Phase N/A
S Sohag University Hospital Sohag

Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital

Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis. The prevalence of thyroid dysfunction in dialysis patients has been reported to range from 20% to 60%, highlighting the need for routine screening and management in this …

13 - 80 years of age All Phase N/A

Role of TIRADS and Bethesda Scoring Systems in Management of Thyroid Nodules

role of TIRADS and Bethesda scoring system in management of thyroid nodules as these methods are ultrasound clasification that helps increase the diagnostic effectiveness of thyroid nodules and reduces the use of preopeative FNA .that nodules are usually divided into diffent categories based on TIRADS and are then referred to …

years of age All Phase N/A
M Man Him, Matrix Fung, MBBS

MWA vs RFA for the Treatment of Moderate-sized Benign Thyroid Nodules

Thyroid nodule is a common condition that affects up to 60% of the population. There is an estimated 10% lifetime probability of developing a thyroid nodule. Although most thyroid nodules are benign, up to 10-15% can enlarge to cause compressive symptoms including neck pressure and discomfort, dysphagia, dyspnea, and dysphonia. …

18 years of age All Phase N/A

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