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Found 884 clinical trials
A Alexandra Marshall

Behavioral Exercise Training to Reduce Cardiovascular Disease Risk

To test the preliminary effectiveness of a home-based exercise training (ET) intervention to improve exercise capacity (VO2 peak & 6-minute walk distance [6MWD]) among prostate cancer (PC) patients compared to controls receiving healthy living education (HLE) at 12 weeks.

40 - 85 years of age Male Phase 1/2
K Ken Bode

Remote Postpartum Blood Pressure Monitoring and Cardiovascular Education

The goal of this clinical trial is to learn if patient education and regular text reminders are a feasible intervention to engage patients and reduce post partum hypertension. The main questions it aims to answer are: Is a structured postpartum remote blood pressure monitoring intervention with education and individualized medication …

18 years of age Female Phase N/A
G Giulio FM Pasca

Feasibility of Innovative Approaches for Personalized Cardiovascular Prevention

The goal of the FITPREV (Feasibility of InnovaTive approaches for personalized cardiovascular PREVention: randomized controlled pilot trial and multidisciplinary evaluation for National Health Service implementation) clinical trial is to study the feasibility of innovative approaches( Polygenic Risk Score and health smartwatch) for personalized primary preventive interventions in cardiovascular diseases (CVD). …

40 - 69 years of age All Phase N/A

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation

Tracheal intubation (TI) is associated with a high risk of adverse events in critically ill patients and peri-intubation hemodynamic collapse is the most commonly observed. The primary aim of the PREVENTION trial is to compare the effect of the pre-emptive use of noradrenaline versus no peri-intubation use of noradrenaline on …

18 - 90 years of age All Phase 3

Evaluation of Cardiovascular Risk Factors in Incident Dialysis Patients

To evaluate the relationships between bone mineral markers levels at dialysis start and vascular calcification progression during a 2 year follow up

18 - 90 years of age All Phase N/A
M Megan McLaughlin, MD, MPH

Text Education About Cardiovascular Health and HIV (TEACH-HIV)

The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).

40 years of age All Phase N/A
K Kerri-Anne Mullen, PhD

Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study

The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary revascularization, stroke, total and cardiovascular mortality). This future study will be the first longitudinal cohort study, to our knowledge, …

25 - 55 years of age Female Phase N/A
D Danusa Damasio, PhD

Effects of Paroxetine on Cardiovascular Function in Septic Patients

It is known that septic shock is characterized by arterial hypotension, decreased peripheral vascular resistance and hyporeactivity to vasoconstrictor agents, with NO being an important mediator of this organ dysfunction. Data in the literature have shown that hyporeactivity to catecholamines is associated with a decrease in the density of α …

18 years of age All Phase 2
B Bri Hihara

Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes

This trial plans to learn more about the effects of a medication, semaglutide, on cardiovascular function, kidney function, and insulin sensitivity in adults with type 1 diabetes. This medication has been effective in reducing cardiovascular disease and diabetic kidney disease and improving glucose control and BMI in adults with type …

18 - 49 years of age All Phase 3

Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs

This study will examine the effect of a healthy diet containing 2 eggs per day compared to a healthy diet containing 3 eggs per week on biomarkers of heart health after 4 weeks.

30 - 60 years of age All Phase 3

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