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Found 1,873 clinical trials
E Erica Hasimoto

Lung Cancer Screening Program Using Low-dose Tomography and Metabolomic Evaluation in a Public Service.

Observational study that aims to evaluate the implementation of a lung cancer screening program in a smoker population included in a public heath service.

45 - 74 years of age All Phase N/A
J Jinhee Seo, RN

Genomic Analysis to Identify a Predictive Biomarker for Immunotherapy

This study is designed to identify the predictive biomarker for immunotherapy using patient samples (tumor tissue, blood, fecal material) who treated with immune checkpoint inhibitor.

18 years of age All Phase N/A
R Rong Zhang

Risk Factors for Postoperative Cough in Patients Undergoing Thoracoscopic Lung Resection

Lung cancer, as the main cause of cancer-related deaths in both males and females, is a great risk to human health. Pulmonary resection is the most applicable to early-stage lung cancer diagnoses and considered the best curative options. Coughing is a prominent symptom among postoperative complications, with approximately 18%-50% of …

18 - 70 years of age All Phase N/A
A Amyn Bhamani

Assessment of Novel Biomarkers in Participants Undergoing Targeted Lung Health Checks

Low-dose CT (LDCT) screening for lung cancer (LCS) has been shown to reduce lung cancer specific mortality in multiple randomised controlled trials. However, although LDCT screening has been demonstrated to reduce cancer- specific mortality, there remain outstanding questions regarding how screening can be implemented. In particular, indeterminate nodules are common, …

55 - 74 years of age All Phase N/A
K Kendra Rowe

Health Education Approach to Lung Screening

Evaluate the impact of the patient navigation program on the proportion of patients who complete lung cancer screening (LCS), defined as undergoing a low dose computed tomography (LDCT)

50 - 80 years of age All Phase N/A
Y Yeon Wook Kim, MD, PhD

Prospective Cohort of Diagnostic Bronchoscopy for Peripheral Lung Lesions

The primary objective is To evaluate the usefulness and safety of advanced guided bronchoscopy for histological diagnosis of peripheral pulmonary lesions. The Secondary objective is to establish a strategy that can most effectively use endoscopes for early diagnosis of lung cancer in a real-world care environment by identifying patient/clinical/image/procedure-related characteristics …

19 years of age All Phase N/A
R Renelle L Myers, MD

Improving Detection of Early Lung Cancer in a Diverse Population (IDEAL) Study

The goal of this trial is to (a) identify people at high risk of lung cancer who would benefit from LDCT screening but are currently ineligible based on current lung cancer screening criteria (b) provide the framework to manage patients with Incidental Pulmonary Nodules (IPNs) with appropriate follow-up based on …

50 - 80 years of age All Phase N/A
D Director of Data Science

An Observational Study on the Assessment of Lung Cancer Using Liquid Biopsy for Collecting miRNA Expression Profile and DNA Methylation Biomarkers.

The purpose of this study is to observe whether miRNA and DNA methylation collected through liquid biopsy can serve as a biomarker for evaluating lung cancer.

18 years of age All Phase N/A
A Alexander Cypro, MD

Next Generation Chest X-Ray Tomosynthesis for Screening of Lung Cancer

The goal of this observational clinical trial is to learn if chest tomosynthesis is a potential alternative to computed tomography for the detection of lung cancer. It will also develop artificial intelligence tools to aid in the diagnosis of lung cancer on chest tomosynthesis images. The main questions it aims …

30 - 85 years of age All Phase N/A

European Real-World Registry for Use of the Ion Endoluminal System

The objective of this study is to collect collect real-world data for the Ion endoluminal system.

18 years of age All Phase N/A

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