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Found 2,250 clinical trials
P Pascal PUJOL

Use of an Ultra-rapid BRCA1/2 Status Screening Test in Diagnostic and Theranostic Indication: Performance and Interest for Patients and Practitioners

The time taken to obtain the results of germline mutations in BRCA1 and BRCA2 has become a major issue in adapting the therapeutic management of patients, particularly those with breast cancer. The time taken to obtain the results of BRCA1/2 tests in routine laboratories with a view to personalised treatment …

18 years of age All Phase N/A
Z Zhimin Shao, M.D.

The Association Between Age-related Peripheral Blood Components and Treatment Efficacy in Breast Cancer

This study is a single-center, prospective/retrospective, observational clinical research designed to compare the differences in peripheral blood components between young and elderly HR+HER2- breast cancer patients, and to identify peripheral blood components that may affect the prognosis of young HR+HER2- breast cancer patients. The study population consists of early-stage HR+HER2- …

18 years of age Female Phase N/A

Application of Patient Blood Management in the Oncology Patient Affected by Breast Cancer

Evaluation of the percentage of transfusions in patients with breast cancer undergoing surgery after preventive treatment with haematinics.

18 years of age Female Phase N/A

Predicting Breast Cancer With the BRAVE System

Breast cancer predominates among cancer diagnoses in Canadian women. It accounts for around 25% of new cases and contributes to 13% of all cancer-related deaths. In 2020, almost 27,400 Canadian women were diagnosed with breast cancer and 5,000 of them died from it. Mammography is still the preferred method for …

18 years of age Female Phase N/A
T Tora Henriksen, PhD

The Effects of HER2 Receptor Signaling on Human Brown Fat Activity

The objective of this observational study is to investigate the significance of the HER2 receptor for brown fat activity in humans. Our preliminary data clearly demonstrates that the ErbB signaling pathway, which includes the HER2 receptor, strongly promotes development and function of cultured human BAT cells. The HER2 receptor is …

18 years of age Female Phase N/A
E Edy Ippolito, Prof

Concomitant Radiotherapy and New Drugs in Metastatic Breast Cancer

The primary objective of the study is to describe the tolerance profile of radiation treatments performed during systemic treatment with new drugs (molecular targeted therapies, immunotherapy, others).

18 years of age All Phase N/A
H H. C. Wu, MD.

Clinical Observational Studies:Integrative TCM and Western Medicine for Breast Cancer

The aim of this study is to investigate the intervention of traditional Chinese medicine (TCM) in managing the side effects experienced by breast cancer patients undergoing conventional Western medical treatments, such as blood cell decline, nausea, vomiting, gastrointestinal discomfort, and overall quality of life. The study aims to establish a …

18 years of age Female Phase N/A
C Cuizhi Geng, M. D.

Efficacy and Safety of Dalpiciclib in Hormone Receptor-positive Advanced Breast Cancer

This study is a multi-center, observational, real-world study. We planned to recruit 420 HR+ locally advanced or metastatic breast cancer patients who had received or had not received prior systemic therapy. All patients included in the analysis were receiving or planning to receive dalpiciclib-containing regimens without restrictions, completely following the …

18 years of age All Phase N/A

CAPIVASERTIB REGULATORY POSTMARKETING SURVEILLANCE IN KOREA

To fulfil the post-approval commitment of MFDS to conduct post-marketing surveillance, this study is designed to assess the known safety profile, identify previously unsuspected adverse reactions and to evaluate the effectiveness of Capivasertib under conditions of routine daily medical practice in Korea.

19 years of age All Phase N/A
C Caroline Sweldens, Doctor

Potential Benefits of Radiotherapy in Prone Position for Breast Cancer Patients: a Planning Study

This study has the purpose to investigate the benefit of treating breast cancer patients in prone position. This treatment is compared to the standard technique in our center (supine position with or without respiratory gating). The investigators want to compare the doses on the organs at risk (heart and lungs) …

years of age Female Phase N/A

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