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Found 919 clinical trials
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Medically Tailored Meals for Cardiovascular Health

This randomized clinical trial (RCT) will investigate novel approaches to enhance effectiveness, engagement, reach, and cost-effectiveness of medically tailored meals (MTM) programs for promoting cardiovascular health, focusing on economically disadvantaged New York City neighborhoods with a disparate burden of multiple cardiometabolic diseases. The main questions the RCT aims to answer …

20 years of age All Phase N/A
S Simon Higgins, PhD

Sitting Interruption and Whole-body Cardiovascular Health

There is strong evidence for the association between sedentary behaviors and cardiovascular diseases such as coronary heart disease and stroke. However, the public currently has no clear guidance on how to limit or interrupt their sedentary behaviors. This study will identify and test the physiological effects of several sedentary behavior …

36 - 55 years of age All Phase N/A
N Nina Stachenfeld

Cardiovascular Disease Risk in Women With Endometriosis

To test the hypothesis that estrogen suppression impairs endothelial dysfunction in endometriosis.

18 - 45 years of age Female Phase N/A
Q Quy Phan, PharmD

Effects of Energy Drinks on Cardiovascular Endpoints

This is a clinical trial looking at the impact of energy drinks on heart related parameters. The study will enroll 3 participants who will be exposed to 8 different interventions.

18 - 40 years of age All Phase 4
S Sabina Frljak, MD, PhD

Cardiovascular Genistein Therapy for Heart Failure Inflammation

This Phase 1b/2a open-label study is designed to assess the safety and efficacy of genistein in patients with heart failure (HF). The investigation will focus on its impact on inflammatory and cardiometabolic biomarkers, as well as its effects on cardiac function and exercise capacity. Blood samples will be collected at …

40 - 80 years of age All Phase 1/2
A Alicia Morgans, MD

CV CARE: CardioVascular Care in PC Patients

This research is being done to test a program to assess and manage reversible cardiovascular (CV) risk factors in participants with prostate cancer starting androgen deprivation therapy (ADT), with the goal of integrating a standardized method into Dana-Farber Cancer Institute clinics for all such participants. The name of the intervention …

18 years of age Male Phase N/A
S Sarah Cottin, PhD

Abertay Tea for Cardiovascular Health During Menopause

The regular consumption of seaweed, as observed in Japan, is associated to a reduced cardiovascular risk and prolonged life expectancy. Interventional studies have shown that brown seaweed consumption can reduce blood pressure, improve glycaemic control and lipoprotein profiles, although this varies with population, dose, duration and the type of seaweed. …

45 - 74 years of age Female Phase N/A
M Maged Costantine, MD, MBA

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

The objective is to conduct a double-blinded randomized controlled trial of atorvastatin vs. placebo among postpartum individuals with hypertensive disorders of pregnancy, to improve cardiovascular risk score postpartum. For this, 76 individuals with hypertensive disorders of pregnancy (HDP) will be randomized to atorvastatin 10mg or placebo, which will be started …

20 - 50 years of age Female Phase 4
A Andrew McHill, PhD

The Influence of Sleep on Cardiovascular Outcomes

The goal of this study is to identify the effects of sleep regularity on cardiovascular regulatory mechanisms. The investigators are hoping to discover if improving the regularity of sleep timing will improve metabolic and vascular health markers. The protocol is a 12-week prospective cohort study that includes both field and …

18 - 40 years of age All Phase N/A
A Anja Lia

Digital Secondary Prevention After Atherosclerotic Cardiovascular Disease

Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality worldwide and in Norway. Approximately 50% of the patients admitted to hospitals with an acute ASCVD event has had a previous event. The high number of patients being readmitted to hospitals with new ASCVD events is to a …

18 years of age All Phase N/A

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