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Found 919 clinical trials
A Agnes Bosch, MD

OCTA in Cardiovascular Disease and Healthy Controls

This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy individuals. The study will be conducted at the Clinical Research Centre (CRC), Department of Nephrology and Hypertension at the …

18 - 75 years of age All Phase N/A
D Duck-chul Lee, PhD

Dose-Response to Resistance Exercise on Cardiovascular Health

A large body of evidence indicates numerous health benefits of physical activity, including prevention of cardiovascular disease (CVD), the leading cause of death in the US. This evidence has led to US Physical Activity Guidelines that recommend ≥150 min/week of moderate or ≥75 min/week of vigorous aerobic exercise (AE), plus …

40 years of age All Phase N/A
M Melissa Hines, MD

Evaluation Of Cardiovascular Health Outcomes Among Survivors 2

Childhood cancer survivors who received certain treatments are at a higher risk of developing heart problems in the future. This study is looking at ways to educate childhood cancer survivors about that risk and encourage them to receive a recommended heart screening test.

26 years of age All Phase N/A
R Renjie Chen, PhD

Acute Effects of Cold Exposure on Cardiovascular System

This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.

18 - 30 years of age All Phase N/A
H Haoxin Gu

Noninvasive Real-Time Arterial Waveform Monitoring for Cardiovascular Disease Assessment

The goal of this observational study is to learn whether noninvasive real-time arterial waveform monitoring can be used to assess cardiovascular diseases in adults. The main question it aims to answer is: Can photoacoustic imaging accurately capture arterial waveforms from patients' fingers? Can features extracted from the arterial waveforms reflect …

18 - 80 years of age All Phase N/A
J Jeremy Spencer, BSc, PhD

Impact of Pomegranate Seed Oil on Postprandial Cardiovascular Disease Risk Markers

Dietary fat plays a crucial role as a modifiable risk factor influencing both non-fasting lipaemia and vascular reactivity. Notably, the intake of dietary saturated fatty acids (SFAs) has been associated with adverse effects on blood lipid profiles, whereas increased consumption of unsaturated fatty acids (UFAs) has shown potential to improve …

- 65 years of age Female Phase N/A
J Jeremy M Kellawan, PhD

The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.

18 - 35 years of age All Phase 4
J Jena Hayes

A Study of Cardiac Rehabilitation Intervention to Improve Cardiovascular Health and Outcomes

A single-group, multi-center, non-randomized clinical trial will be conducted to assess the feasibility of implementing an enhanced virtual world-based cardiac rehabilitation (VWCR) program within a muti-site clinical trial.

18 years of age All Phase N/A
P Philippe MENASCHE, MD, PhD

Treatment of Non-ischemic Cardiomyopathies by Intravenous Extracellular Vesicles of Cardiovascular Progenitor Cells

The goal of this clinical trial is to assess the safety and efficacy of three intravenous injections of the extracellulat vesicle-enriched secretome of cardiovascular progenitor cells in severely symptomatic patients with drug-refractory left ventricular (LV) dysfunction secondary to non-ischemic dilated cardiomyopathy. The main questions it aims to answer are: Are …

18 - 80 years of age All Phase 1

Impact of Assessment and Management of Comorbidities in Internal Medicine on Cardiovascular Risk

The aim of assessing and managing cardiovascular risk is to avoid, limit or delay cardiovascular morbidity and mortality. Planned internal medicine hospitalization is developed around the management of cardiovascular risk in patients at high cardiovascular risk, whether in primary prevention or secondary prevention. During planned hospitalization, patients benefit from comprehensive, …

18 years of age All Phase N/A

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