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Found 2,256 clinical trials
C Christian Laflamme, PhD

Long-term Safety of Nipple Sparing Mastectomy in Women With GPV in Breast Cancer

Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as to whether it is safe to do so. Relative to traditional or skin sparing mastectomy (SSM) techniques, nipple …

18 - 90 years of age Female Phase N/A

Long-Term Follow-up Study of Early Stage Breast Cancer Patients Included in GEICAM Studies

This is a multicenter, cohorts study to collect information from patients diagnosed with early-stage invasive breast cancer who have been previously included in a neoadjuvant or adjuvant clinical trial of the GEICAM group. Patients will be included in this study from the moment of completion of the follow-up of the …

18 years of age Female Phase N/A
X Xin-Wu Cui, PhD,MD

Identification of Benign and Malignant Breast Nodules Using Ultrasound-modulated Optical Tomography: A Multicenter Study

Ultrasonic light scattering imaging is a new functional imaging technology that combines traditional B-mode ultrasound imaging and light scattering tomography (DOT). It can improve the accuracy of early diagnosis of breast cancer based on the characteristics of abnormal blood supply and oxygen consumption of lesions. This study aims to evaluate …

18 - 85 years of age Female Phase N/A
D Dominique GENRE, MD

Database of Data Collection

For several years, the Paoli-Calmettes Institute has been centralizing the retrospective collection of clinical data of patients operated on for histologically proven breast cancer.

18 years of age Female Phase N/A

National Mammography Database

The National Mammography Database (NMD) leverages data that radiology practices are already collecting under federal mandate by providing them with comparative information for national and regional benchmarking. Participants receive semi-annual feedback reports that include important benchmark data such as cancer detection rates, positive predictive value rates and recall rates. Participation …

2 - 99 years of age All Phase N/A

Breast Cancer BRAs Study (Breast Cancer Biomechanics of Radiotherapy And Surgery)

This study, delivered by Portsmouth Hospitals University NHS Trust in conjunction with the Research Group in Breast Health at the University of Portsmouth [1], aims to assess whether it is possible to test breast biomechanics in women who have had surgery with or without radiotherapy for the treatment of breast …

18 years of age Female Phase N/A
A Atiye KAŞ ÖZDEMİR, Lecturer, PhD

Sexual Functıon in Young Women After Breast Cancer Surgery

The aim of this observational study was to analyse sexual function in young women after breast cancer surgery. The main question it aims to answer is Sexual function in young women after breast cancer surgery changes during the one-year follow-up period. Participants will answer demographic information, Female Sexual Function Scale, …

18 - 50 years of age Female Phase N/A
J Jan Žatecký

Localization of Breast Cancer with the Sirius Pintuition Magnetic Seed

A prospective pilot study in the Czech Republic examining the use of magnetic seed Sirius Pintuition for the localization of non-palpable malignant breast tumors and pathological lymph nodes.

18 - 99 years of age All Phase N/A
R Rohini A Hawaldar, BSc

A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer

To understand the effects induced by acute hypoxia that sets in during surgery in breast cancer. To study this, clinical samples (Tumor biopsies) will be obtained during the surgery after partial devascularisation (sample B) and stored for future genomic and proteonomic evaluations.

18 years of age Female Phase N/A
D Dominique GENRE, MD

Real Time Molecular Analysis of Breast Cancer Receiving Neo-adjuvant Chemotherapy

The present project aims at identifying robust candidates for drug resistance in BC patients eligible for NAC. Its originality lies upon the combination of three different and complementary prospective approaches: from the molecular analyses of biopsies sampled before and after NAC, from in vitro BC Patient-Derived Organoids (PDO) mimicking patient's …

18 years of age Female Phase N/A

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