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Found 1,621 clinical trials

Multicenter Study of Fulminant Type 1 Diabetes in China

This study took FT1D(fulminant type 1 diabetes) as the research object, collected the cases of FT1D patients, and described the clinical characteristics of this type of disease. The HLA susceptibility genes of FT1D were identified by PCR and other techniques, taking age-sex-matched healthy subjects as controls and HLA genes as …

years of age All Phase N/A
P Philippe Klee, MD-PhD

Anhydroglucitol in Children With Type 1 Diabetes

The investigators will measure blood levels of 1,5-anhydroglucitol in children with type 1 diabetes and correlate them with parameters related to functional beta-cell mass in diabetic patients. The values will be compared to those obtained in healthy volunteers. Children with newly diagnosed diabetes as well as children with longstanding disease …

2 - 18 years of age All Phase N/A
L Lucie Radovnická

Effect of HCL Insulin Delivery System on Glycemic Control in Patients With T1D

The goal of this study is compare the effect of hybrid closed loop system (HCL) for automatic insulin dosing treatment on the glycemic control of type 1 diabetes (T1D) in patient with different initial glycated hemoglobin.

18 years of age All Phase N/A

24-hour Movement Behaviors in Adults With Type 1 Diabetes

Only 24.9% of the Belgian adults (25-50 years) with type 1 diabetes mellitus (T1DM) achieve a good glucose control. This can be explained by the challenging day-to-day diabetes management which places a substantial burden on this population. However, a tight glycemic control is fundamental in order to prevent the development …

25 - 50 years of age All Phase N/A
S Sara Tehrani, MD, PhD

The MIND Study - Microangiopathy IN Diabetes

This clinical investigation will evaluate two contactless optical devices based on spatial frequency domain and laser speckle technology for quantification of the skin micro-circulation in patients with diabetes mellitus type 1.

18 - 60 years of age All Phase N/A
I Ioannis- Anargyros Vasilakis, PhD

Effect of Advanced Hybrid Closed Loop System, MiniMed 780G in Newly Diagnosed Children and Adolescents With Type 1 Diabetes on Glycemic Control and Patient Reported Outcomes Compared to Standard Insulin Therapy Historical Data (AHCL in New Onset T1D Children Study)

The objective of this study is to evaluate glycemic control of users of the AHCL system MiniMed 780G with GS4 calibration-free sensor in children and adolescents with newly diagnosed T1D implemented directly upon T1D diagnosis in combination with continuous glucose monitoring system (CGMS) compared with those treated with MDI retrieved …

7 - 17 years of age All Phase N/A
K Karen Ko

HLA Demographics Study in Adults With Type 1 Diabetes

This is a study to evaluate the HLA-DRB1*04:01 genotype in adults that have been diagnosed with type 1 diabetes

18 - 45 years of age All Phase N/A
F Fumihiko Urano, MD

Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study

In this study, the investigators hypothesize that studying monogenic variants with strong effect associated with severe insulin deficiency of Wolfram syndrome will provide important insights into the more complex type 1 and type 2 diabetes mellitus. Aim 1. Establish and maintain a registry of patients with Wolfram syndrome. An Internet …

years of age All Phase N/A
C Catherine Beauchemin, PhD

Societal Burden Associated With Type 1 Diabetes in Canada

The purpose of this observational study is to estimate the burden of T1D on caregivers of patient with T1D in terms of work productivity, healthcare resource utilization and quality of life.

18 years of age All Phase N/A

Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy

Predicting early onset neuropathy in people with type 1 diabetes

18 - 60 years of age All Phase N/A

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