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Found 1,595 clinical trials
C Claus B Juhl, MD, PhD

Type 1 Diabetes and Diabetes Distress

The goal of this clinical trial is to reduce diabetes distress in emerging adults (18-35 years) with type 1 diabetes and moderate-to-severe diabetes distress. The expectation is that a group-based psychological intervention (ACTnow) will not only reduce diabetes distress but also improve psychological well-being and glycemic outcomes. The intervention involves …

18 - 35 years of age All Phase N/A
M Mette J Rothmann, PhD

Use of an Online Intervention for the Treatment of Diabetes Distress in Patients With Type 1-Diabetes

This study will investigate whether an online intervention can be helpful in reducing diabetes distress in people with type 1 diabetes and elevated diabetes distress, compared to individual counselling sessions (online, phone-based or face-to-face, depending on the preference of the person with type 1 diabetes). Half of the participants will …

30 years of age All Phase N/A

Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy

Predicting early onset neuropathy in people with type 1 diabetes

18 - 60 years of age All Phase N/A
N Neha Sudhir

Game-based Pediatric Diabetes Education

The goal of this study is to evaluate the impact of a mobile app video game called Digital Vaccine for Type 1 Diabetes (DVx-T1D)™, proposed as a low-risk, non-invasive, digital therapeutic candidate for behavior change in children 6 to 12 years of age with Type 1 Diabetes (T1D). The investigators …

6 - 12 years of age All Phase N/A
J Jenna Duffecy, PhD

CBTi for the Treatment of Insomnia in Type 1 Diabetes

The goal of this study is to learn if treating insomnia with a therapy intervention in people with type 1 diabetes will help to better control sugar levels, sleep, and quality of life. The questions this study aims to answer include: Will this intervention help the insomnia symptoms? Will obtaining …

18 - 65 years of age All Phase 0
J Jennifer Warnick, PhD

Type 1 Diabetes Adolescents for Healthier Lifestyles Study

Before the 1990s, obesity was rare among young people with type 1 diabetes (T1D), but now it is more common. Recent studies show that over 50% of young people with T1D will have overweight or obesity within five years of being diagnosed with T1D. Both obesity and T1D increase the …

13 - 18 years of age All Phase N/A

Exploring Skin Barrier Function, Recurrence of Diabetes Device-Related Contact Dermatitis and Evaluation of Hydrocolloid and Silicone-Based Patches for Its Prevention in Children and Adolescents With Type 1 Diabetes

The goal of this clinical trial is to ensure that contact dermatitis is not prohibiting any person with diabetes the access to the optimal treatment. The main questions this study aims to answer are: How many pediatric patients with contact dermatitis due to diabetes devices experience recurrence of contact dermatitis …

2 - 18 years of age All Phase N/A
S Seong-Ho Heo, MD

Comparison of Intensive Versus Standard Care & Education for Dyslipidemia in Hypertension and Diabetes Patients

The prevalence of dyslipidemia is high among patients with hypertension and diabetes mellitus, which increases the risk of cardiovascular disease. However, many patients lack awareness and adherence to treatment and lifestyle modifications. Therefore, a more structured and intensive approach to management and education is required. This study aims to implement …

30 - 80 years of age All Phase N/A
O Orianne OV Villard, MD

Efficacy of Islet Re-transplantation After Failure of Beta-cell Replacement

Islet transplantation and pancreas transplantation are established therapeutic options for selected individuals with type 1 diabetes experiencing severe glycemic instability and recurrent hypoglycemia. Although these approaches significantly improve glycemic management and quality of life, long-term graft survival remains limited, with a progressive decline in beta-cell function over time. The clinical …

18 years of age All Phase N/A
M Mikael Huhtala, M.D., Ph.D.

Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics

The goal of this observational study is to compare fetal liver ultrasound radiomics between pregnancies complicated by type 1 diabetes and healthy controls. The main questions it aims to answer are: Are fetal liver ultrasound radiomic features reproducible? Does fetal liver ultrasound radiomics differ between pregnancies complicated by type 1 …

18 - 45 years of age Female Phase N/A

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