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Found 61,726 clinical trials

Cultural Adaptation of Drug Treatment for DJJ Youth

This project aims to improve the understanding of the impact of Ethnic and Racial Discrimination (ERD) on adolescent alcohol and other drug use (AOD) within the Black Justice-Involved Youth (JIY) population. Individual interviews with Black JIY and focus groups with parents and guardians of Black JIY and community members who …

12 - 17 years of age All Phase N/A

Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers

This is a multi-centre, randomised, non-inferiority, phase III study in patients with low risk differentiated thyroid cancer. Patients will be identified via oncology multidisciplinary team meetings. There will be two sources of patients in the trial, with the same histological diagnoses and prognosis (i.e. recurrence risk): Group 1: Patients who …

16 years of age All Phase N/A
S Sven Dittrich, Prof.

Prospective Evaluation of Univentricular Hearts

Univentricular heart defects are among the most complex congenital malformations. The treatment of these patients usually includes 3 operations and accompanying diagnostics, some of which are invasive, within the first 3 to 4 years of life until the "fontan circulation" is established. Unfortunately, the group of patients with a univentricular …

6 - 60 years of age All Phase N/A
A Alessandro FARNE, Dr

A Technical Innovation of Prismatic Adaptation Test in Healthy Subject, in Favour of Autonomy and Independence in Daily Life Following a Brain Injury

Unilateral neglect is a neuropsychological disorder reflected by a disturbance in the spatial exploration and distribution of directed attention affecting the contralateral part of space and body relatively to the brain lesion. The chronic aspect of this pathology leads to a poor progression following rehabilitation and a decreased independence of …

18 - 70 years of age All Phase N/A
S Sarah Bourne

SCORE Emerging Adult Cannabis Use & Stress

The interface between cannabis use and stress is a particularly important focus for sex differences research in emerging adults. Given the dynamics at play in this critical stage when cannabis use is most prevalent, developmentally informed research is needed to guide tailored clinical interventions. This study will apply rigorous and …

18 - 25 years of age All Phase 1/2
J Juan Antonio Díaz-Mancha, PhD

Effectiveness of Diaphragm Treatment in Reducing Low Back Pain

Objective: Determine the benefits of including a Stretching technique of the anterior part of the diaphragm in the supine position in the conventional physiotherapy treatment protocol applied to insurance company patients with mechanical low back pain. design: The aim is to carry out an experimental, analytical, prospective, longitudinal, randomized, single-blind …

18 - 50 years of age All Phase N/A
V Vratislav Strnad, MD

Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours

The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected patients where salvage surgery with clear resection margins was not possible.

18 years of age All Phase N/A
B Bing Sun

Efficacy and Safety of LT3001 on Treating the Acute Ischemic Stroke

This phase II clinical study is designed to evaluate the safety and efficacy of LT3001 in the treatment of acute ischemic stroke

18 - 80 years of age All Phase 2
M Moishe Liberman, MD

Validation of a System Using Aerosol Glycerine to Detect and Localize Intraoperatively Pulmonary Air Leaks

Air leaks represent one of the most common complications and postoperative morbidity in thoracic surgery. Air leaks have been associated with the largest preventable morbidity associated with increased costs following lobectomy (typically related to increased length of stay). However, the standard used to detect and localize the air leaks, the …

18 years of age All Phase N/A
S Suzanne Finucane

Powered Prosthesis for Use With TF Osseointegration Recipients

The purpose of this study is to evaluate functional mobility, control, and user satisfaction from persons who have an amputation above the knee and have received osseo-integration (OI) and targeted muscle reinnervation (TMR) surgery, while walking with a powered knee and ankle prosthesis.

18 - 70 years of age All Phase N/A

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