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Found 63,122 clinical trials
M Michele Bartoletti, MD

Antimicrobial Combination Therapy for Treatment of Enterococcus Faecalis Bacteremia

Prospective, multicenter, national, observational pharmacological study on the evaluation of efficacy of appropriate monotherapy vs combination treatment for non-complicated Enterococcus faecalis (EF) bloodstream infection (BSI) and identification of gut microbiota fingerprint of patients with EF-BSI correlated to antimicrobial treatment and clinical outcome

18 years of age All Phase N/A
N Nigel Lou, PhD

Study of Student Flourishing

The goal of this study is to learn how a science-based mobile app, called Flourish, affects student well-being. The main questions it aims to answer are: Does receiving access to the Flourish app increase well-being (e.g., positive affect, loneliness, belonging) among students? Does using the Flourish app in combination with …

18 years of age All Phase N/A
H Hongguo Dai

Phase III Clinical Trial of SHPL-49 Injection in the Treatment of Acute Ischemic Stroke

This study is designed to determine the efficacy and safety of SHPL-49 intravenous infusion in acute ischemic stroke patients.

18 - 80 years of age All Phase 3

AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer

This trial is a Phase III study. The purpose of this study is to evaluate the efficacy and safety of AK112 and chemotherapy versus bevacizumab and chemotherapy for the first-line treatment of metastatic colorectal cancer.

18 - 75 years of age All Phase 3
F Fabio Giuseppe Pagella, MD

Adenoidectomy: Correlation Between Individual Factors, Surgical Technique, and Residual Adenoids

Adenoidectomy is the most commonly performed otolaryngological surgical procedure in children. The removal of adenoid lymphoid tissue is intended to clear the nasopharynx and restore the patency of the nasal airways. In most cases, adenoidectomy leads to an improvement in symptoms and quality of life. However, in some patients, symptoms …

- 18 years of age All Phase N/A
X Xu LIU, MD

A RWS of SC MTX in Chinese RA Patients

Design: A prospective, single-arm, multicenter, real-world study that does not interfere with the patient's treatment plan Primary Objective: 1\. To evaluate the effectiveness and safety of subcutaneous Methotrexate (MTX) in RA patients in a real-world setting; Exploratory Objectives: To assess the safety and effectiveness of subcutaneous MTX in RA patients …

18 years of age All Phase N/A
T Tiebang Liu, Ph.D.

TEEM-GIFTS: A Gamified mHealth to Reduce Post-Discharge Suicide Risk

Patients with mental disorders are at significantly higher risk of suicide after discharge compared to the general population and patients with other diseases. Currently, there is a lack of post-discharge community suicide risk management services in China. The research team's preliminary research suggests that mHealth interventions are well-accepted and feasible …

18 years of age All Phase N/A
Y Yannick HOURMANT

Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients.

The purpose of this study is to demonstrate the efficacy of early continuous intravenous infusion of hypertonic saline solution (HSS) to improve survival and independence in daily life activities (at 6 months) of patients with traumatic brain injury at high risk of intracranial hypertension.

18 - 75 years of age All Phase 3
A Andrew Lee, MHA

Clinical Biospecimen Collection

New York Cancer and Blood Specialists(NYCBS) is dedicated to provide world-class, patient-centered, affordable care to patients with cancer and blood disorders in their own communities, close to family and friends. Our vision is a world free of cancer and blood disorders by contributing to the search for cures by offering …

18 years of age All Phase N/A

A Study to Evluate Efficacy and Safety of HRS-8080 Combined With Dalpiciclib in Patients With Advanced or Metastatic Breast Cancer Resistant to Adjuvant Endocrine Therapy.

The study is being conducted to evaluate the efficacy and safety of HRS-8080 combined with dalpiciclib versus fulvestrant combined with dalpiciclib in patients with locally advanced/metastatic breast cancer who had developed drug resistance to prior adjuvant endocrine therapy.

18 - 75 years of age Female Phase 3

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