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Found 1,598 clinical trials

ED Diabetes Screening and Outpatient Care

This goal of this NIH funded R01 study is to identify risk factors for not being able to follow-up for a new diagnosis of diabetes in the emergency department and improve linkage of these newly diagnosed patients to appropriate outpatient care. Its three aims will be accomplished through 1) a …

20 - 70 years of age All Phase N/A
F Faming Zhang, MD, PhD

Washed Microbiota Transplantation for Type 1 Diabetes Mellitus

This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patients with Type 1 Diabetes Mellitus (T1DM).

3 - 100 years of age All Phase N/A
I Ivana Dedinska, prof, MD, PhD.

Predicting Outcomes in Posttransplant Diabetes Mellitus Via microRNA

The study aims to improve the prediction and early detection of post-transplant diabetes mellitus (PTDM) in kidney transplant recipients. The investigators are investigating whether specific microRNA profiles measured 3 months after transplantation can reliably predict the development of PTDM within the following one to two years. Additionally, the investigators are …

18 years of age All Phase N/A
G Gianna L Wilkie, MD

Early Detection of Gestational Diabetes Mellitus in Pregnancy

The purpose of this study is to develop an implementation protocol and test the feasibility and acceptability of a first trimester screening protocol for the early detection of gestational diabetes mellitus (GDM).

18 years of age Female Phase N/A

Continuous Glucose Monitoring, Diabetes Education, and Peer Support for Management of Uncontrolled Type 2 Diabetes

This research study is investigating whether a diabetes virtual group visit program using a continuous glucose monitor (CGM) can help improve glucose levels and quality of life in individuals with uncontrolled type 2 diabetes. People in the study will join group visits virtually to discuss using CGM, understanding CGM, and …

18 years of age All Phase N/A

Investigating How NNC0487-0111 Regulates Insulin of Adults With Type 2 Diabetes

The purpose of this clinical study is to find out how NNC0487-0111 affects, how the body uses insulin (a hormone that helps the body control blood sugar) and how well the pancreas works in people living with type 2 diabetes. There are 2 study treatments. Participants will get either NNC0487-0111 …

18 - 75 years of age All Phase 1
J Joseph Rutter

Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes

Sulfonylurea medications are unsafe for older patients with diabetes. They are associated not only with hypoglycemia, but also with falls and increased cardiovascular risk. Yet they continue to be prescribed frequently. Indeed, older adults with type 2 diabetes, who are especially prone to adverse effects, are more likely to be …

45 years of age All Phase N/A
J Jennifer A Campbell, PhD, MPH

CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes

Prediabetes affects over one-third of adults in the United States, placing them at a higher risk for developing type 2 diabetes and heart disease, which can lead to serious health complications and increased medical costs. Although a program called the Diabetes Prevention Program (DPP) has been shown to lower the …

18 years of age All Phase N/A
M Michelle Lagares

A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity

The goal of this clinical trial is to learn if AT673 contributes to additional weight loss and glycemic control when given with semaglutide in participants with overweight/obesity and type 2 diabetes. The main questions it aims to answer are: To compare the effect on body weight of two doses of …

18 years of age All Phase 2

Faecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus

SUMMARY Rationale The(small) intestinal microbiota composition has been implicated to play an important role in (human) metabolism, as well as autoimmune diseases such as type 1 diabetes mellitus. Faecal microbiota transplantation (FMT) has been shown to significantly alter the microbiota composition, without any serious side-effects. It was recently demonstrated that …

18 - 45 years of age All Phase 2

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