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West Mifflin, Pennsylvania Clinical Trials

A listing of West Mifflin, Pennsylvania clinical trials actively recruiting patient volunteers.

Found 553 clinical trials

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

The purpose of this study is to determine the safety, feasibility, recommended dose(s) and regimen(s) of JNJ-87704916 as monotherapy and in combination with cetrelimab.

18 years of age All Phase 1
D Danielle Black, MPH

Triheptanoin for Children With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency

This is a medical research study to test a medication in patients with a disease called Pyruvate Dehydrogenase Complex (PDC) Deficiency. The medication is triheptanoin, which is currently FDA approved for the treatment of Long-Chain Fatty Acid Oxidation Disorders. Previous research suggests that triheptanoin may also be effective in the …

1 - 17 years of age All Phase 1
M Maureen Morgan

Effect of a Wrist-worn Device That Produces a Small Vibration on Sleep and Performance That Can Occur During and After Night Shift Work

The overarching goal of this research study is to determine "proof of concept" of effect of a non-invasive sleep aid device on sleep and performance during sleep opportunities (naps) that occur during and after simulated night shift work. Aim 1: To determine the effect of the ApolloNeuro device on sleep …

18 years of age All Phase N/A
E Emily G Thomas, BA

Mindfulness Training and Respiration Biosignal Feedback - Study 2

The goal of this research is to test usability and user satisfaction with a new breathing feature on the meditation app, Equa, to help young adults who are distressed, understand their physiological responses and mindfulness skill development during meditation. Our main aims are to test an algorithm that can use …

18 - 30 years of age All Phase N/A
A Anne-Marie Rick, MD, MPH, PhD

Digital Maternal Support Tool Implementation

The goal of this trial is to learn if a smartphone app designed to provide postpartum support is acceptable to new mothers in Pennsylvania. The main questions it aims to answer are: How easy is the app is to use? Does the app meet the needs of new parents? Is …

18 - 45 years of age Female Phase N/A
E Eleanor Shirley, MA

Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting

The goal of this clinical trial is to validate the safety and effectiveness of a two-stage approach for minimally invasive craniofacial soft tissue reconstruction using autologous fat grafting in wounded service members and veterans. The main questions it aims to answer are: Will treating subjects with post-traumatic craniofacial deformities using …

18 years of age All Phase N/A
N Nikitha Deepak

Evaluation of the PPAL

This research study is being done to better understand the impact of the PPAL assisted toileting device. The PPAL consists of a powered, height adjustable commode chair with integrated transfer boards. The system is designed to allow the user to assist with their own transfers to/from bed or chair to …

18 years of age All Phase N/A
A Amy Rose, RN, BSN

Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma

This translational study will examine the immune effector responses of patients who received a two-drug combination for first line therapy by examining tumor and peripheral blood of participants with unresectable locally advanced or metastatic melanoma.

18 years of age All Phase N/A
A Amber Pereira, M.A.

Social Threat, Adolescent Relationships, and Suicidality Study

In recent years, adolescents are having higher rates of emotional health problems, such as suicidal thoughts and behaviors (STBs). The goal of this study is to learn about how teens' attention to different types of information relates to their real-world relationships and their emotional health. The investigators hope this study …

12 - 17 years of age Female Phase N/A
A Amy Rose, RN, BSN

9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)

This is a study of the combination of 9 ING-41 (elraglusib) and retifanlimab plus mFOLFIRINOX in patients with pancreatic cancer without prior systemic therapy for advanced disease. The safety lead-in cohort will consist of 6 patients, followed by dose de-escalation if necessary, based on safety assessments. After evaluating the safety …

18 years of age All Phase 1

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