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Philadelphia, Pennsylvania Clinical Trials

A listing of Philadelphia, Pennsylvania clinical trials actively recruiting patient volunteers.

Found 1,618 clinical trials

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells. This is done either by killing the cells or by stopping them from growing. The purpose of this study is to …

18 years of age Female Phase 4
M Madi E Leach, Bachelors of Science

Motivation for Daily Living Skills

The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults. Here are the main questions the trial aims to answer: Can this trial improve motivation to complete daily living skills for skills that people know how …

16 - 25 years of age All Phase N/A
K Karen Smith

Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

The current protocol is to determine the biodistribution, metabolism, excretion and brain uptake of 18F-JSS20-183A. The goal of this radiotracer is to quantify 4Repeat Tau (4Rtau) protein that is abnormally deposited in the brain of people with a class of neurodegenerative diseases called tauopathies, such as Progressive Supranuclear Palsy (PSP), …

40 - 85 years of age All Phase 0
S Stephanie Cummings

The Neuralert Stroke Monitor Pilot Trial

This trial aims to demonstrate that the Neuralert Monitoring System will detect strokes before they would be identified by current standard of care. Each patient will be monitored for up to five days, depending on device connectivity or battery duration. Each monitoring session will consist of wearing a Neuralert device …

22 years of age All Phase N/A
L Lillias Maguire, MD

Topical Anti-Androgens in Pilonidal Sinus Disease

The goal of this randomized clinical trial is to test the topical drug clascoterone in patients with pilonidal disease, which is a common, benign skin condition of the gluteal cleft. The main questions it aims to answer are: Does clascoterone improve the severity of pilonidal disease as scored by a …

18 years of age All Phase 2
S Shonda Sumner, BSN

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

The clinical schedule will consist of 3 injections of CD40.HIVRI.Env (VRIPRO) at weeks 0, 4, and 24.40 volunteers without HIV and in overall good health, aged 18 to 60 years, who previously participated in the HVTN 706 trial.

18 - 60 years of age All Phase 1
D Daniel J Lee, MD, MS

Intravesical Treatment of Bladder Cancer at Home, Multi-modal Treatment Support

The proposed project will have two separate cohorts. The first will be to perform a more in-depth qualitative assessment of the barriers and facilitators for treatment compliance for non-muscle invasive bladder cancer. The second arm will be to create and test a BCG at home program. Participants in the second …

18 years of age All Phase N/A
K Kinge-Ann Marcelin

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

This clinical trial evaluates the usefulness of using a smartphone-based HIV-specific smoking cessation intervention at the time of lung cancer screening in helping people living with HIV quit smoking. Positively Smoke Free - Mobile may help patients with HIV quit smoking.

45 - 80 years of age All Phase N/A
S Sonia Read

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

Patients with Parkinson's disease (PD) sometimes experience symptoms affecting their movement, such as slowness, tremor, stiffness, and balance or walking problems. Many patients also have other symptoms not related to movement, called non-motor symptoms, which may affect one's mood or emotions, memory or thinking, or cause one to see or …

40 years of age All Phase 4
G Gregory Alfaro

LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study

The purpose of the LCAT (Lecithin cholesterol acyl transferase) Natural History Study (LCAT NHS) is to help identify people with a mutation in a gene called LCAT, collect and store information about their medical history and disease course, and to assess for associations and follow changes in clinical features and …

years of age All Phase N/A

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