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Drexel Hill, Pennsylvania Clinical Trials

A listing of Drexel Hill, Pennsylvania clinical trials actively recruiting patient volunteers.

Found 1,051 clinical trials
G Gabriel Kass, M.A.

Ketone Ester Intervention in Alcohol Use Disorder

The purpose of this research is to study how a nutritional ketone ester may effect brain function and alcohol consumption in regular alcohol users. The study will see how the brain responds, once after drinking the ketone ester and once after drinking a "placebo", which will look and taste the …

21 - 65 years of age All Phase 2/3

SBRT With Atezo/Bev for HCC

A phase I dose escalation and pharmacodynamic study of repeated dose stereotactic body radiotherapy (SBRT) administered with concurrent atezolizumab and bevacizumab for patients with advanced hepatocellular carcinoma (HCC)

18 - 99 years of age All Phase 1

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

The objective of this study is to measure the acceptability and impact of the progestin implant on frequency of vaso-occlusive crises, quality of life, and hematologic parameters in women with SCD.

18 - 45 years of age Female Phase 4
J Jeffrey I Joseph, DO

Respiratory Monitoring System That Detects & Predicts OIRD

This study is being conducted to evaluate the ability of the Respiratory Monitoring System (RMS) to detect and predict opioid induced respiratory depression (OIRD) in post-operative surgical patients managed with opioid medications. The ability of the RMS to detect OIRD will be compared to the detection of OIRD using a …

18 years of age All Phase N/A
J Janet Audrain-McGovern, Ph.D.

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

This study aims to investigate harm-reduction sampling in a choice format versus medicinal nicotine sampling on smoking behavior, identify mechanisms of sampling's effects, and explore moderators of these effects among a national sample of people unmotivated to quit smoking. Participants will be randomized 2:1 to choose one of three harm-reduction …

21 years of age All Phase N/A
M Maria Prociuk

Neurofeedback to Treat Depression - 2

This study tests the efficacy of a new psychotherapeutic strategy for reducing negative attention bias (and therefore depression severity) in participants with MDD. This real-time fMRI neurofeedback therapy uses cloud-based pattern classification to decode a patient's attentional state and dynamically modulate task stimuli (in a closed loop) based on this …

18 - 65 years of age All Phase N/A

Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

Phase II, open-label, single-arm study of CD40/Dectin-1 immunotherapy as maintenance treatment in patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not progressed following 4-6 months of first line (1L) chemotherapy.

18 years of age All Phase 2
S Stephen T Famularo

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

Acute respiratory distress syndrome (ARDS) is a serious and potentially life-threatening lung condition that can affect children. Currently, ventilator settings commonly used in treatment are based on approaches developed for adults, and it remains unclear whether these settings are equally effective for children. Because children's bodies respond differently than adults', …

38 - 17 years of age All Phase 2
L Leeya F. Pinder

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

This clinical trial evaluates the use of self-collected vaginal samples for human papillomavirus (HPV) testing in patients referred for a colposcopy and/or cervical excisional procedures to improve cervical cancer prevention. HPV is a common virus which usually causes infections that last only a few months, but sometimes can last longer. …

25 years of age Female Phase N/A
K Kaiyu Ma Clinical research regulatory specialist, PhD

Comparing Numbing Techniques in Mohs Micrographic Surgery

This study seeks to determine whether adjunct regional nerve blocks reduce pain and anxiety in adult patients undergoing Mohs micrographic surgery for face and scalp skin cancers. Participants will be randomized to one of two arms: (1) placebo regional nerve block with sterile normal saline or (2) adjunct regional nerve …

18 years of age All Phase N/A

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