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Bethel Park, Pennsylvania Clinical Trials

A listing of Bethel Park, Pennsylvania clinical trials actively recruiting patient volunteers.

Found 389 clinical trials

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

To Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis.

18 - 75 years of age All Phase 3

Cortical Excitability in Cyclic Vomiting Syndrome

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS).

18 - 60 years of age All Phase N/A
M Marc N Coutanche, PhD

Cognitive and Affective Mechanisms Underlying an Olfactory Approach to Modify Cigarette Craving

The proposed study uses fMRI and behavioral measures in and outside the laboratory to investigate the neurobehavioral mechanisms underlying the impact of pleasant olfactory cues (OCs) on cigarette craving. The investigators plan to randomize 278 participants to a pleasant OC condition or an odor blank (neutral) condition and due to …

18 - 49 years of age All Phase N/A

Characterization of Gastric Evoked Potentials

This is an exploratory study that will determine and standardize how best to record gastric evoked potentials (GEPs) elicited by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS), by optimizing the TMS parameters and cortical sites necessary to evoke GEPs.

21 - 60 years of age All Phase N/A
D Debbie E Harrington, BS

Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation

The purpose of this research study is to see how well a new type of myoelectric prosthesis works. A myoelectric prosthesis is a robotic limb for amputees that is controlled by sensing the activity of muscles in the body above the amputation level. This study involves a medical procedure to …

22 - 70 years of age All Phase N/A
R Rhonda Dahlstrom

Promising ROd-cone DYstrophy Gene therapY

This is a two-step, multicenter, Phase I/II study including an open-label dose-escalation phase (Step 1) and a three-arm controlled double-masked randomized extension phase (Step 2), in subjects with advanced RCD due to a mutation in the RHO, PDE6A, or PDE6B gene.

18 years of age All Phase 1/2
K Kai Yu, Ph.D.

Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound

Neuromodulation is a fast growing field that offers a wide range of applications for both understanding and treating the brain. Future research for non-invasive neuromodulation will need to elucidate the optimal frequency, duration, and intensity of stimulation for a variety of technologies and diseases. Closed loop stimulation is thus a …

18 - 64 years of age All Phase N/A
D Diana Gilmore

IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

The purpose of this study is to assess the safety and tolerability of two 5-day infusion cycles of IV gallium in adult patients with CF who are infected with NTM. Funding Source - FDA Office of Orphan Products Development (OOPD)

18 years of age All Phase 1
C Courtney Perry

Concussion Treatment in Older Adults

The purpose of this study is to conduct the first randomized control trial for targeted treatments for concussion in adults 50 years or older. Participants will be enrolled at their first concussion clinical visit (V1) and their second study visit will occur after (up to 7 days) or concurrently with …

50 - 99 years of age All Phase N/A
S Study Coordinator

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

The study is a multi-center, un-blinded, randomized control study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.

18 years of age All Phase 3

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