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Bethel Park, Pennsylvania Clinical Trials

A listing of Bethel Park, Pennsylvania clinical trials actively recruiting patient volunteers.

Found 389 clinical trials
J Jared W Magnani, MD

Mobile Health Program for Rural Hypertension

Hypertension (HTN) is the leading modifiable cause of cardiovascular disease. Rural individuals experience challenges of the rural health divide: geographic distance from providers, social isolation, limited social resources, and high rates of low health literacy. This study evaluates a home-based blood pressure monitoring (HBPM) program that provides longitudinal health education, …

18 years of age All Phase N/A
K Kymberly Young, PhD

Amygdala Neurofeedback for Depression - Large Scale Clinical Trial

The goal of this study is to evaluate whether rtfMRI-nf training to increase the amygdala response to positive memories may serve as a stand-alone intervention for major depressive disorder

18 - 55 years of age All Phase N/A
T Taylor Lust

Reduced-dose Botox for Urgency Incontinence Among Elder Females

The purpose of this study is to study the treatment of urgency urinary incontinence (UUI), specifically among women 70 years and older, by comparing reduced versus standard dose of onabotulinumtoxinA (BTX; trade name BOTOX(c)) injection in the bladder.

70 years of age Female Phase 1/2
V Vishwajit L Nimgaonkar, MD PhD

Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness

This is a hybrid1, effectiveness-implementation study of yoga-based exercises (YE) as an adjunctive tool for rehabilitation among persons with Severe Mental Illness (SMI). The two-arm randomized controlled trial will compare the efficacy of YE compared to the Wellness Lifestyle Program (WLP). Primary outcomes of the study will be self-report and …

18 - 65 years of age All Phase N/A
J Jude Jonassaint, RN

PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD

The purpose of this study is to find objective biomarkers of vaso-occlusion (blood vessel blockage) in people with SCD. Using information from earlier studies and work being done, researchers have developed a strategy to image VOC, using positron emission tomography (PET). The ability to see and measure VOC in SCD …

18 years of age All Phase 1
M Maribeth A Wesesky, BPS

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

This is a double blind adjunctive randomized controlled trial for schizophrenia using cromoglicate.

18 - 65 years of age All Phase 1/2
D David J Kolko, PhD

SKIP for PA Study: Team and Leadership Level Implementation Support for Collaborative Care

In a prior application (MH064372), the investigators' treatment research program (Services for Kids In Primary-care, SKIP) developed and tested a chronic care model-based intervention, called Doctor Office Collaborative Care (DOCC), that was found to be effective in the management of childhood behavior problems and comorbid ADHD. In the "SKIP for …

18 years of age All Phase N/A
K Kristine Wilckens, PhD.

Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

Dementia caused by Alzheimer's disease affects approximately 5.6 million adults over age 65, with costs expected to rise from $307 billion to $1.5 trillion over the next 30 years. Behavioral interventions have shown promise for mitigating neurodegeneration and cognitive impairments. Sleep is a modifiable health behavior that is critical for …

65 - 85 years of age All Phase N/A
J John Moore

Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

Single center, randomized, placebo- controlled study to assess change in mucociliary clearance of moderate to severe asthma patients after treatment with dupilumab or placebo.

18 years of age All Phase 4
W William Evans, PhD

Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for …

18 years of age All Phase 2

Simplify language using AI