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Lyndhurst, Ohio Clinical Trials

A listing of Lyndhurst, Ohio clinical trials actively recruiting patient volunteers.

Found 615 clinical trials

Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

This randomized, controlled, pivotal study is intended to determine whether up to ten sequential 24-hour treatments with the Selective Cytopheretic Device (SCD) will improve survival in patients with Acute Kidney Injury (AKI) requiring continuous kidney replacement therapy (CKRT) when compared to CKRT alone (standard of care). This study is further …

18 years of age All Phase N/A
K Katrina Clinical Research Coordinator

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA; 600mg/m2 body surface area per dose about every 12 hours) and (2) pharmacokinetically-guided precision-dosing of MMF (MMFPK; MMF dosed twice daily to achieve an area under the …

8 - 20 years of age All Phase 2
K Kaelan Chan

Nectero EAST System Clinical Study

The purpose of this randomized clinical trial is to treat patients with small to mid-sized abdominal aortic aneurysms (AAA), maximum diameter of 3.5 cm to 5.0 cm, using a locally delivered, single-dose endovascular treatment. The main question the study aims to answer is to demonstrate efficacy of the product for …

21 - 85 years of age All Phase 2/3
E Edward V Maytin, MD, PhD

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

The purpose of this study is to better understand the immune response to basal cell carcinoma (BCC) treated with Photodynamic Therapy (PDT) in order to develop new methods of treating BCC. Previous research suggests that PDT alters the immune response, possibly in a way that could promote better tumor clearance …

18 years of age All Phase 2
T Tina Craig

CERAMENT™| Bone Void Filler Device Registry

A device registry to compile data on the performance of CERAMENT BONE VOID FILLER in normal use.

18 years of age All Phase N/A

Safety and Tolerability of Open-Labeled Iloperidone in Adolescents

To evaluate the safety and tolerability of iloperidone in adolescent patients with schizophrenia or bipolar I disorder for up to 52 weeks of treatment.

12 - 17 years of age All Phase 4
S Site Public Contact

Spine Radiosurgery for Symptomatic Metastatic Neoplasms

The purpose of this study is to compare three types of radiation therapy for cancer that has spread to the spine. The two types of radiation therapy used in this trial are External Beam Radiation Therapy (EBRT) and Stereotactic Body Radiation Therapy (SBRT). EBRT delivers tightly targeted radiation beams from …

18 years of age All Phase 2
N Neeti Galwankar

Pelvic Health Electrically Evoked Recording (PEER) 2 Study

To collect physiological signals at several timepoints during the therapy evaluation period.

18 years of age All Phase N/A
S Site Public Contact

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

The goal of this clinical trial is to study the safety and tolerability in all advanced solid tumors, including advanced urothelial carcinoma. The main question\[s\] it aims to answer are: Is FX-909 safe and tolerable, as a monotherapy and in combination with Pembrolizumab What is the right dose level for …

18 years of age All Phase 1
A Albert Yim

Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing

The purpose of this clinical trial is to assess the safety and efficacy of AM3101 to facilitate meniscal repair and reduce the incidence of non-healing complications and morbidities associated with a failed meniscal repair. This is a prospective, randomized, controlled, double-blinded, multi-center study.

18 - 40 years of age All Phase 1/2

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