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Lakewood, Ohio Clinical Trials

A listing of Lakewood, Ohio clinical trials actively recruiting patient volunteers.

Found 514 clinical trials
M Matteo Trucco, MD

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

The purpose of this study is to test the safety of combining the disulfiram (DSF) and copper gluconate (Cu) to liposomal doxorubicin to treat patients with sarcomas that recurred or did not respond to initial treatment.

1 years of age All Phase 1
X Xiaojuan Li, PhD

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. …

18 - 50 years of age All Phase N/A
K Kevin L Kilgore, Ph.D.

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury

This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS

17 years of age All Phase N/A

Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis

The purpose of this research is to support the clinical value of the Cionic Neural Sleeve for individuals diagnosed with multiple sclerosis (MS).

22 - 75 years of age All Phase N/A
K Kayela Arrotta, PhD

Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

The goal of this clinical trial is to learn if new educational program prior to epilepsy surgery can either decrease the risk of cognitive decline after surgery or be a help to those patients who experience a decline after undergoing epilepsy surgery. Participants will participate in 2 individual virtual sessions …

18 - 60 years of age All Phase N/A
P Peter Leo BS, RN

Low Voltage-Directed Catheter Ablation for Atrial Fibrillation

A two-pronged approach to evaluate long term success of non-paroxysmal ablation when using a: specified low voltage-directed with pulmonary vein isolation (LD+PVI) approach compared to , an approach of pulmonary vein isolation (PVI) alone.

18 - 85 years of age All Phase N/A
M Maimanivanh (Mary) Phiakhamta

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

Medicines that reduce the amount of testosterone in the body are commonly used to treat prostate cancer. PRL-02 depot is a potential treatment for men with advanced prostate cancer. It is given by an injection into the muscle. Men with advanced prostate cancer can take part in this study. Their …

18 years of age Male Phase 1
S Sherri Brandsen

Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study in combination with etoposide for subjects with relapsed/refractory neuroblastoma.

- 31 years of age All Phase 2
H Haily Sappington

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

The primary objectives of Cohort A Phase 1b and exploratory expansion are to evaluate the safety and tolerability of TTI-101 orally administered as a single agent to participants with locally advanced or metastatic, and unresectable Hepatocellular Carcinoma (HCC) and to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 …

18 years of age All Phase 1/2
M Melissa Schmitt, RN

Peripheral Interfaces in Amputees for Sensorimotor Integration

The purpose of this research is to gather information on the safety and effectiveness of an implanted wireless sensory enabled highly intuitive controlled prosthetic device.

21 years of age All Phase N/A

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