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New York, Bronx, New York Clinical Trials

A listing of New York, Bronx, New York clinical trials actively recruiting patient volunteers.

Found 2,251 clinical trials

A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment

The purpose of this study is to find out whether the fat ALT flap procedure is a safe and practical option for reducing neck morbidity in HNSCC patients following cancer treatment of the neck. Neck morbidity after radiation therapy and surgery includes difficulty swallowing, neck or shoulder pain, stiffness, swelling, …

18 years of age All Phase N/A
A Aidan Rogers, MS

Neuro Device for Aphasia

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

18 - 80 years of age All Phase N/A

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

The goal of this interventional clinical trial is to learn about TNG260, a CoREST inhibitor, in combination with pembrolizumab in patients with advanced solid tumors with a known STK11 mutation. The main question[s] it aims to answer are: the recommended dose for Phase 2 to evaluate the safety and tolerability …

18 years of age All Phase 1/2
V Victoria Roselli

Treatment of Low-Risk Submassive Pulmonary Embolism With FlowTriever

This study is focused on investigating the efficacy and safety of the FlowTriever device to treat low-risk submassive pulmonary embolism.

18 years of age All Phase N/A

Vaccination With Flt3L, Radiation, and Poly-ICLC

This is a combination of 4 therapies, three of which are used to treat a single "target site" of your cancer (such as a lymph node or a single tumor), and the 4th is given directly into the blood stream (intravenous or "IV"). Radiation: The target site --lymph node or …

18 years of age All Phase 1/2
S Sheeraz Qureshi, MD, MBA

ESP Block in MIS Lumbar Spine Surgery

This is a prospective, randomized controlled trial of patients undergoing minimally invasive transforaminal lumbar interbody fusion. This study will randomize patients into one of two groups: erector spinae plane (ESP) block and no ESP block.

18 - 80 years of age All Phase N/A
P Phase 1 Screening

A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies

This is a Phase 1/2, multicenter, open-label (unless otherwise specified in a combination-specific module) study of DCC-3116 in combination with anticancer therapies. Modules within the master protocol are defined according to different combinations of DCC-3116 with other anticancer agents.

18 years of age All Phase 1/2
F Frances Lara

XTX301 in Patients With Advanced Solid Tumors

This is a first-in-human, multicenter, Phase 1, open-label study designed to evaluate the safety and tolerability of XTX301 as monotherapy in patients with advanced solid tumors.

18 years of age All Phase 1

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

The proposed project tests the efficacy of glutamate modulators in non-depressed individuals with alcohol use disorder (AUD); the primary hypothesis is that the glutamate modulator being tested reduces heavy drinking days compared to the active control. It also aims to investigate, using a 2 by 2 factorial (2x2) design, the …

21 - 70 years of age All Phase 2
K Karina Ziskovich

Radiofrequency Ablation Study in LatinX Patients

Benign thyroid nodules can still create cosmetic, compressive, or hormonal issues for patients. In the past, surgery was typically used to treat thyroid nodules causing the above issues through partial or complete thyroidectomy. More recently, minimally-invasive techniques have been developed to treat these issues. This study is investigating the use …

18 - 90 years of age All Phase N/A

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