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Kew Gardens, New York Clinical Trials

A listing of Kew Gardens, New York clinical trials actively recruiting patient volunteers.

Found 1,927 clinical trials

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer

This is a multicenter, Phase 1b/2 trial. The phase 1b part of the trial aims to determine the RP2D of elacestrant when administered in combination with alpelisib, everolimus, palbociclib, abemaciclib, and ribociclib. The Phase 2 part of the trial will evaluate the efficacy and safety of the various combinations in …

18 years of age All Phase 1/2
G GV20 Therapeutics

A Study of GV20-0251 in Patients With Solid Tumor Malignancies

This is a Phase 1 study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

18 years of age All Phase 1
P Pragya Yadav, Ph.D.

Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study

The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed with 1.0-1.5 cm margins.

19 - 90 years of age Female Phase 2

A Study of Glofitamab and Lenalidomide in People With Mantle Cell Lymphoma

The purpose of this study is to find out whether the combination of glofitamab and lenalidomide is an effective treatment for relapsed or refractory Mantle Cell Lymphoma

18 years of age All Phase 1
S Sari Feldman

MTC Versus FMT in for RCDI

Investigating four different treatment of MTC or FMT

18 years of age All Phase 1
S Steven Levine, MD

Digital Equity for Stroke Approach

A community-academic partnership composed of a State University of New York (SUNY) Downstate Health Sciences University inter-disciplinary team of scientists (representing public health, medical informatics, vascular neurology/stroke center) and the Digital Equity Community Advisory Board (DECA) will guide our research. This is an NIH R21 pilot study. Our Specific Aims …

18 years of age All Phase N/A

A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain

The purpose of this study to see how the brain absorbs, distributes, and gets rid of tucatinib in people who have HER2+ cancers (breast cancer, NSCLC, CRC, or GEC) that have spread to the brain, and to learn more about how cancer cells develop resistance to treatment. The researchers will …

18 years of age Female Phase 2
P Paula Busse

Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents

This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.

6 - 17 years of age All Phase 2

Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology

At present, it is not clear whether performing a hip arthroscopy at the same time as a PAO improves patient outcomes after surgery compared to a PAO alone. This research project will randomize patients to receive either a PAO alone, or a PAO and a hip arthroscopy at the same …

16 - 50 years of age All Phase N/A

A Study of Pembrolizumab and Radiation Therapy in People With Mesothelioma

The purpose of this study is to find out whether IMPRINT in combination with pembrolizumab is a safe treatment for people with malignant pleural mesothelioma (MPM).The highest dose of IMPRINT that causes few or mild side effects when given in combination with pembrolizumab will be found. Once the highest safe …

18 years of age All Phase 1

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