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Bronx, New York Clinical Trials

A listing of Bronx, New York clinical trials actively recruiting patient volunteers.

Found 3,065 clinical trials
O Oncology Clinical Research Referral Office

Pembrolizumab and Lenvatinib in Advanced Cervical Cancer

This is a phase II trial of combination therapy of pembrolizumab and lenvatinib in patients with locally advanced or metastatic cervical cancer that had failed first line of therapy. The hypothesis is the combination of lenvatinib and pembrolizumab will overcome vascular endothelial growth factor (VEGF)-mediated immunosuppression to enhance the response …

18 years of age Female Phase 2
K Keoni Fordham

TTVR Early Feasibility Study

The objective of this early feasibility study is to gain early clinical insight into the performance of the Intrepid transcatheter tricuspid valve replacement (TTVR) system intended for transfemoral access to deliver a self-expanding bioprosthetic valve within the tricuspid valve.

18 years of age All Phase N/A
M Melissa Johnson, MD

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Phase 1 aims to determine the Maximum Tolerated Dose (MTD) and identify the Recommended Phase 2 Dose (RP2D) to be used in phase 2.

18 years of age All Phase 1/2
A Aiden Brossfield

Hypoparathyroidism Natural History Study

This is a prospective three-year natural history study of adults with hypoparathyroidism. The goal is to monitor patients with hypoparathyroidism to define end-organ damage in the context of the disease. The study objectives are to: Build a prospective cohort of patients to study HPT-associated end-organ damage. Determine end-organ physiologic consequences …

18 - 100 years of age All Phase N/A
E Elie Ramly, MD

Craniomaxillofacial and Upper Extremity Allotransplantation

The purpose of this study is to evaluate functional and aesthetic outcomes of combined facial and upper extremity composite tissue allografts on patients who have not achieved functional and aesthetic outcomes with conventional reconstructive surgical strategies and prosthetic devices.

18 - 64 years of age All Phase N/A
D Douglas S Mennin, PhD

Brief Interventions for Coping with Distress

This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training, and 3) a health and wellness education training.

18 - 65 years of age All Phase N/A
L Lauren Winterbottom, MS

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

The purpose of this study is to develop and test the hardware and software components of the MyHand-SCI device to assist with hand function for individuals with C6-C7 spinal cord injury.

18 years of age All Phase N/A
P Pragya Yadav, Ph.D.

De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You

This is a live biobank study for breast cancer (BC) patients where samples will be collected at inflection points in the course of the disease.

18 - 90 years of age Female Phase N/A

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

This study will test the safety and effectiveness of a combination of pembrolizumab, olaparib, and temozolomide to see how well these drugs work when given together in people with a glioma that either did not respond to previous treatment or came back after treatment.

18 years of age All Phase 2

Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment

The purpose of this study is to develop and test a new magnetic resonance imaging (MRI) technique to see if it can be used to tell the difference between tumor growth from worsening of cancer and growth from the effects of treatment in participants who have brain tumors treated with …

18 years of age All Phase N/A

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