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Springfield, New Jersey Clinical Trials

A listing of Springfield, New Jersey clinical trials actively recruiting patient volunteers.

Found 148 clinical trials
G Gayathri Subramanian

Reducing Pain From Wisdom Molar Extractions

This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken …

18 - 64 years of age All Phase 2

Combinatory Rehabilitation Used for Substantially Helping Individuals With Traumatic Brain Injury

New learning and memory impairment (NLMI) is a common and devastating manifestation of TBI associated with substantial life burdens. Persons with moderate to severe TBI have shown improvement in NLM for prose material (e.g. story) as well as beneficial changes in default-mode network (DMN) activation during list-learning19 following treatment with …

18 - 65 years of age All Phase 1
K Kai Sucich, MA

MRI Markers of Feedback Timing During Learning in Individuals With TBI With and Without Clinical Depression

The goal of this proposal is to examine the influence of feedback timing on learning and brain function in individuals with moderate-to-severe traumatic brain injury (TBI), with and without depression.

18 - 65 years of age All Phase N/A
M Moti Ramgopal, MD

A Clinical Trial of STP0404 in Treatment-Naïve Adults With HIV-1 Infection

The purpose of this study is to evaluate the antiviral effect, safety, tolerability, and pharmacokinetics of STP0404 in treatment naïve adult participants living with Human Immunodeficiency Virus Type 1 (HIV-1) infection.

18 - 65 years of age All Phase 2
M Mridula A. George

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

This study proposes that the addition of statins reduces the treatment delays or early discontinuations secondary to cardiotoxicity in patients with Stage I-III HER2 positive breast being treated with anti-HER2 therapy.

18 years of age Female Phase 2
J Jessica Reynolds

The Acute Burn ResUscitation Multicenter Prospective Trial

This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.

18 years of age All Phase N/A
F Freddrenia Holms

A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease

This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess safety, tolerability, pharmacokinetics, and efficacy of ONO-2020 in participants with mild to moderate Alzheimer's disease (AD). This study aims to determine whether administering ONO-2020, an epigenetic regulator, may improve cognitive functions like memory and cognition in individuals with Alzheimer's …

55 - 85 years of age All Phase 2
J Jamie Han

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

The purpose of this study is to determine whether BHV-7000 is effective in the treatment of idiopathic generalized epilepsy with generalized tonic-clonic seizures and includes an additional open-label extension (OLE) phase.

18 - 75 years of age All Phase 2/3
R Rebeca Costa

Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study

This study seeks to conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.

18 - 65 years of age All Phase N/A

Robotic Balance Training to Improve Postural Control and Balance Post-Traumatic Brain Injury

The purpose of this study is to assess a balance training program to see if it can be helpful to improve balance and avoid falls in people who have had traumatic brain injuries (TBIs). The study will involve three groups of research subjects: 1) TBI-intervention group, 2) TBInon -intervention group …

18 - 65 years of age All Phase N/A

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