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Palisades Park, New Jersey Clinical Trials

A listing of Palisades Park, New Jersey clinical trials actively recruiting patient volunteers.

Found 3,070 clinical trials

Community Safety and Violence

This study will describe, estimate, and explore the effectiveness of community-centered safety models (CCSMs)-including co-response, alternative response, and community violence intervention modalities-implemented across U.S. municipalities to prevent community violence among youth and young adults (YYA). Specifically, the investigators will (1) describe CCSM implementation using implementation-science methods, (2) estimate CCSMs' impacts …

years of age All Phase N/A
O Oruka Investigative Site

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

This is a multicenter, randomized, double-blinded, placebo-controlled, dose-range finding study to evaluate the efficacy and safety of ORKA-002 in adult participants with moderate-to-severe plaque psoriasis.

18 - 79 years of age All Phase 2
H Himani Bhatt, DO

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established peri-operative pain regimen used for total knee replacement surgery will effect pain control. Does Suzetrigine given pre-operatively decrease the total opioid consumed after total …

18 - 85 years of age All Phase 3

A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults

The specific aim of this study is to examine the Safety, Tolerability and Pharmacokinetic of Semaglutide Nasal Spray compared with placebo and positive control in Adult Overweight or Obese Participants.

18 - 65 years of age All Phase 1

Neuromuscular Electrical Stimulation in Foot and Ankle Surgery

This is a pilot randomized controlled trial, wherein the intervention group will undergo NMES five days a week beginning three weeks postoperative and lasting for ten weeks. Both the control and intervention groups will start standard physical therapy six weeks postoperative. Primary outcome measure will be the isometric strength of …

18 - 70 years of age All Phase N/A
M Martha Cavallo, PNP

Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV

This is a Phase I/II, multi-site, open-label, single arm study to describe the pharmacokinetics (PK) and safety of glecaprevir/pibrentasvir (GLE/PIB) initiated during pregnancy in women with hepatitis C virus (HCV) infection (acute or chronic) with or without HIV and to evaluate safety for their infants through 10 weeks postpartum.

16 - 45 years of age Female Phase 1/2
Q Quetzal Therapeutics Investigator

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

This Phase 3 study in adult participants with newly diagnosed low-risk APL will evaluate the efficacy, safety, and PK of an oral capsule formulation of ATO, in combination with ATRA.

18 - 71 years of age All Phase 3

Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer

In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with intermediate-risk prostate cancer receiving standard stereotactic body radiotherapy (SBRT).

years of age Male Phase 3
C Christopher Quiocho

Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness

The investigation is intended to evaluate the safety and effectiveness of the AlphaReturn Blood Management System when used in conjunction with the cleared AlphaVac MMA F1885 System for the treatment of acute pulmonary embolism.

18 years of age All Phase N/A
M Matthew Dobbs

Neutralizing Interleukin (IL)-6

The proposed study aims to establish the feasibility and safety of subcutaneous tocilizumab, a monoclonal antibody (mAb) against interleukin (IL)-6 receptor, in adults with Major Depressive Disorder (MDD) and evidence of peripheral immune activation. IL-6 is a pro-inflammatory cytokine implicated in the pathophysiology of depression. The investigators hypothesize that neutralizing …

18 - 70 years of age All Phase 2

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