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Belleville, New Jersey Clinical Trials

A listing of Belleville, New Jersey clinical trials actively recruiting patient volunteers.

Found 350 clinical trials
R Robyn Gartrell, MD, MS

Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors

This phase I trial tests the safety, side effects, and best dose of ex vivo expanded natural killer cells in treating patients with cancerous (malignant) tumors affecting the upper part of the brain (supratentorial) that have come back (recurrent) or that are growing, spreading, or getting worse (progressive). Natural killer …

1 - 38 years of age All Phase 1

Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury

The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect blood pressure. The main questions are: How does stimulation affect blood pressure over the year? What …

18 - 75 years of age All Phase N/A
J Jorge Chavez, BS

Treatment of Orthostatic Hypotension in SCI

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

18 - 60 years of age All Phase 4
R Research Manager

Upper Extremity Training for Chronic Cervical Spinal Cord Injury

This study is to understand how the combination of activity-based recovery training and targeted spinal cord transcutaneous stimulation (scTS) can improve participants' ability to use their hand, arms, and core.

18 years of age All Phase N/A
L Leighann Martinez, Research Manager

Self-balancing Personal Exoskeleton for SCI (Site 2)

This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).

18 years of age All Phase N/A

A Study of BGB-B3227 Alone and in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors

This is a first-in-human (FIH), open-label, multicenter dose escalation and expansion study of BGB-B3227, a humanized immunoglobulin G1 (IgG1) antibody. The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BGB-B3227 as a monotherapy or in combination with tislelizumab with or …

18 years of age All Phase 1

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

This is a first-in-human (FIH), Phase 1a/1b, open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-T187 alone and in combination with other therapeutic agents in participants with advanced solid tumors.

18 years of age All Phase 1
K Kate Chervin

Improving Walking After a Lower Limb Injury Using a Custom Motorized Orthosis

The purpose of this research study is to assess the ease, convenience, and efficacy of walking when using a motor powered ankle foot orthosis (AFO) brace, in adults who have had a lower limb injury.

18 - 80 years of age All Phase N/A
Y Yeraz Markarian, PhD

OBWELL: Innovative Psychotherapeutic Intervention to Treat Postpartum Depression

Postpartum Depression (PPD) is defined as depression that occurs after childbirth, with intense symptoms that last longer than "baby blues". PPD differs greatly from "baby blues", a term used to describe the typical sadness, worry and tiredness that women experience after childbirth, which often resolves within a week or two …

18 years of age Female Phase N/A
F Fideliza Perez

MMRC Horizon One Adaptive Platform Trial Evaluating Therapies in RRMM

This trial is an adaptive platform trial. The structure of the protocol allows the trial to evolve over time. Multiple investigational arms will be included within the trial under a Master Protocol (MP). These investigational arms may be added as appendices at different times depending on whether they are trial-ready …

18 - 99 years of age All Phase 2

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