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Raleigh-Durham, North Carolina Clinical Trials

A listing of Raleigh-Durham, North Carolina clinical trials actively recruiting patient volunteers.

Found 495 clinical trials
M Michelle McCall

Intraoperative OCT Guidance of Intraocular Surgery II

The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes. The investigators believe this technology will enable novel ophthalmic and other microsurgeries not possible due to current limitations in surgical …

4 years of age All Phase N/A
W William M Bullock, MD, PhD

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade. English speaking American Society of Anesthesiologists (ASA) 1-3 patients ages 18-80 receiving prolonged interscalene nerve block will be randomized into 3 groups: first group receiving a …

18 - 80 years of age All Phase N/A
K Kalyn Purnell

Patient Specific Talus Spacer Post Approval Study

Humanitarian Device Exemption Approved Patient Specific Talus Spacer Post Approval Study.

21 years of age All Phase N/A

Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

The purpose of this study is to assess the functional outcomes in patients undergoing proximal femur resection and reconstruction with an endoprosthesis, based on the abductor muscle repair technique. The investigators hypothesize that those patients who receive reattachment of the abductors directly into the prosthesis will have better functional outcomes …

16 - 75 years of age All Phase N/A

Bempedoic Acid Pregnancy Surveillance Program

Bempedoic acid pregnancy surveillance program

18 years of age Female Phase N/A
N NIEHS Join A Study Recruitment Group

Investigating the Impact of Obesity on Pubertal Development in Girls

Background Studies suggest that overweight girls may be developing breast tissue, and therefore starting puberty, earlier than normal weight girls. However, it is hard to distinguish breast tissue from fatty tissue. Researchers think that by using breast ultrasound, among other tests, they can do a better job of telling whether …

8 - 14 years of age Female Phase N/A
A Amira Al-Uzri

Anesthetics and Analgesics in Children

The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

- 17 years of age All Phase N/A
R Rachel Greenberg, MD

Pharmacokinetics of Drugs Administered to Children

This is a prospective study of children <21 years of age with the goal of characterizing the PK of drugs administered per standard of care as prescribed by the treating caregiver.

- 20 years of age All Phase N/A
T Tey Ching Siong

Pediatric Post-Approval Registry

This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatment of moderate or severe obstructive sleep apnea (OSA). Implanted subjects will be followed for 5 years post-implant.

18 - 21 years of age All Phase N/A
M Misty Prince

STRIVE Post-Market Registry Study

This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-market setting.

18 years of age All Phase N/A

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