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Durham, North Carolina Clinical Trials

A listing of Durham, North Carolina clinical trials actively recruiting patient volunteers.

Found 582 clinical trials
M Michelle Ward

Intestinal Microbiome Transplant in ALS

This is a 24-week study of intestinal microbiome transplant in people with ALS. All participants will be evaluated clinically in person for 4 visits. Blood and mailed/ fresh stool samples will also be collected. Blood samples will be used to determine changes in neurofilament light chain over time. Stool samples …

18 years of age All Phase 1/2
H Hannah L Weisbecker, BS

The Validation Study of Bioelectronics

The purpose of this study is to investigate the safe wearability and basic functions of the multi-modality sensors fabricated in the PI lab.

18 - 99 years of age All Phase N/A
S Samuel A Alvarez-Falcon, MD

Virtual Reality Visual Field Testing as an Alternative in Childhood Eye Disease

The purpose of this study is to test a new way of measuring the peripheral vision (called a visual field test) using a device which can be worn as goggles rather than being a large instrument the patient must sit at. This new visual field test (called VisuALL) is an …

4 - 21 years of age All Phase N/A
T Tanya Dorff, MD

Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes

This is a Phase 2, randomized two-armed, multi-site study of 138 patients with metastatic castrate sensitive prostate adenocarcinoma. Patients will be randomized 1:1 to receive the fasting mimicking diet, or usual diet. All patients will receive standard of care treatment for their prostate cancer. The fasting mimicking diet will be …

years of age Male Phase 2
J Jaslyn Grullon

Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equity

Background Inequalities in COVID-19 infection, hospitalization, and death in under-studied, under-represented, and under-reported groups of people are severe. A growing number of studies have assessed the impact of individual risk factors. But few studies have assessed which factors are the greatest drivers of COVID-19 disparities from a wider perspective. Objective …

18 - 100 years of age Female Phase N/A
N NIEHS Join A Study Recruitment Group

Immune Cell Response to Stimuli

This study will investigate the response of immune cells (neutrophils, monocytes) to various signals in the test tube to determine how they sense the signals in the body and what substances they produce in response to them. It will determine how the cells may, under certain circumstances, contribute to inflammation, …

18 - 65 years of age All Phase N/A

Medtronic Cardiac Surgery PMCF Registry

This registry is being conducted to support ongoing post-market surveillance activities.

years of age All Phase N/A
K Katherine Uyhazi, MD, PhD

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

This is an international, multicenter study with two components: Registry A standardized genetic screening and a prospective, standardized, cross-sectional clinical data collection Enrollment is open to all genes on the RD Rare Gene List Natural History Study A prospective, standardized, longitudinal Natural History Study Enrollment opens gene-by-gene, based on funding …

4 years of age All Phase N/A
P Paula Vanderford, MD

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.

years of age All Phase N/A
J Jennifer Talbert, MS, RN

Pharmacokinetics of Off Label Pediatric Medications

The purpose of this study is to measure the level of medicines found in body fluids such as blood, urine, spinal fluid of children.

1 - 8 years of age All Phase N/A

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