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Townsend, Maryland Clinical Trials

A listing of Townsend, Maryland clinical trials actively recruiting patient volunteers.

Found 764 clinical trials
E Esther Oh, MD, PhD

HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms

This randomized controlled trial study aims to evaluate a revised hearing care intervention for older adults with Alzheimer's Disease and Related Dementias (ADRD). The community-delivered hearing care intervention utilizes tailored strategies to assess impact on communication, neuropsychiatric symptoms (NPS), and care partner distress.

60 - 100 years of age All Phase N/A
A Alicia Cooke, MS

Phase 4 of Designed With You

The purpose of this study is to provide evaluate the feasibility of a structured 8-10-week, multi-component intervention that integrates individualized resource navigation, personalized self-care planning, emergency and end of life (EOL) preparedness, and peer support to improve the well-being, resource access and social connectedness of caregivers with disabilities. For this …

18 years of age All Phase N/A
S Sam Rudow

Ketorolac Effects on Post-operative Pain and Lumbar Fusion

A double blind prospective randomized trial of IV ketorolac vs. placebo in management of patients undergoing lumbar one or two level spinal fusions.

18 - 85 years of age All Phase 4

A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight

The purpose of this study is to evaluate the efficacy and safety of retatrutide compared with placebo for body weight reduction. Participation in the study will last about 65 weeks and may include about 18 visits.

18 years of age All Phase 3
A Anthony J Gonzalez, BS

Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2

This proposal aims to understand the neurobiological mechanisms of fatigue in individuals with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). This knowledge will eventually provide candidate mechanisms to target with pharmacological intervention and inform rehabilitative care for those individuals suffering from symptoms of fatigue in PASC.

18 - 75 years of age All Phase N/A
D Dr. Ronald Goldwater, MDCM, M.Sc(A), CPI

A Study to Investigate HLA-G Targeted Exosome (SOB100) in Healthy Subjects

The investigational drug, SOB100, is an HLA-G targeted exosome equipped with a nanobody namely anti-HLA-G VHH on the exosome membrane. This is a Phase I dose escalation study to exam the tolerability, safety, and pharmacokinetics in healthy subjects.

18 years of age All Phase 1
J Joshua M Roberts, PhD

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

This study is designed to establish the foundation for a new therapy for neurofibromatosis Type I (NF1)-related cutaneous neurofibromas (cNFs) by assessing the feasibility and efficacy of IMLYGIC in adults with NF1 and cNFs who desire local treatment of their cNF due to disfigurement, progression, pain, itching or other concerns. …

18 years of age All Phase 1
A Anna E Phillips, MD, MS

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic Pancreatitis (CP). QST uses a specific series of standardized stimulations to map the pain system. …

18 years of age All Phase N/A
D David B Yaden, PhD

Effects of Psilocybin in Obsessive Compulsive Disorder

This study will test the feasibility, safety, and evidence for efficacy of psilocybin administration in participants with obsessive compulsive disorder (OCD). This will serve as a preliminary proof of concept study for future larger studies aimed to investigate the utility, cognitive mechanisms, and neural correlates of this intervention.

21 - 70 years of age All Phase N/A
A Anthony J Gonzalez, BS

Behavioral and Neural Representations of Subjective Effort Cost

The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical …

18 - 35 years of age All Phase N/A

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