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Waltham, Massachusetts Clinical Trials

A listing of Waltham, Massachusetts clinical trials actively recruiting patient volunteers.

Found 2,403 clinical trials

Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares

This is a randomized, multicenter, double-blind, single administration study to investigate the efficacy and safety of 2 dosing regimens of Purified Cortrophin® Gel in the treatment of an acute gouty arthritis flare. The study consists of three periods: an optional pre-screening period, a double-blind treatment period, and a 7-day follow-up …

18 - 90 years of age All Phase 4
D Daniel Lee

Modulation Effect of tACS on Chronic Low Back Pain

Investigating the modulation effect of tACS

18 - 60 years of age All Phase 2
A Alexandra J Berger Eberhardt, MD

A Trial of Self-Adjusted Nitrous Versus Placebo During Office Vasectomy

The goal of this clinical trial is to see if nitrous oxide is safe and effective to use during during vasectomies performed in a clinic/in-office setting. This trial will compare self-administered nitrous oxide versus a placebo (oxygen) during office vasectomy. The main questions it aims to answer are: Whether self-administered …

18 - 85 years of age Male Phase 0
A Anna Fratello

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic surgery.

years of age All Phase 2
A Ana-Maria Vranceanu, PhD

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

The purpose of the present investigation is to test the efficacy of a virtual, brief (6 sessions) dyadic (patient and care-partner together) intervention to prevent chronic emotional distress in dyads where one person is diagnosed with Young Onset Dementia (YOD). Through this study, we seek to address the unmet need …

18 - 65 years of age All Phase N/A
A Alessandra Anzolin, PhD

Linked Outcomes in Various EEG-Hyperscanning Setups

The goal of this observational study is to investigate how brains of healthy controls respond when they interact with their romantic partner compared to when they interact with a stranger. The main goals are: Explore how two people's brains interact with each other by recording brain activity at the same …

20 - 60 years of age All Phase N/A
J Jennifer Stamps, PhD

Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

The VR-CARES project is an innovative, collaborative effort that invites dementia care professionals into the design process of a virtual reality platform seeking to mitigate their work-related burden and social isolation by cultivating a virtual community of support. The co-created, caregiver-specific VR platform will serve as a safe, communal space …

18 years of age All Phase N/A
R Rachel Rodgers, PhD

Body Acceptance After Baby Intervention

The purpose of this study is to learn if a novel online single-session intervention can help improve body dissatisfaction in new moms. The active intervention condition, Body Acceptance After Baby (BABI), uses acceptance-based skills to help participants cope with body dissatisfaction. BABI will be evaluated against another active intervention condition …

18 years of age Female Phase N/A
T Timothy Clinton

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

This prospective, interventional, open-label, phase 3 randomized study evaluates a multimodal analgesia discharge pathway to reduce automatic opioid prescribing following routine robotic-assisted laparoscopic prostatectomy (RALP). Patients are counseled on post-operative pain management and then may opt into or out of the study with randomization to discharge prescriptions including (A) multimodal …

45 years of age Male Phase 3
G Gabriela Hobbs, MD

Momelotinib During and After HCT in Myelofibrosis

This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT).

18 years of age All Phase 1

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