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Waltham, Massachusetts Clinical Trials

A listing of Waltham, Massachusetts clinical trials actively recruiting patient volunteers.

Found 1,797 clinical trials
M Michelle Stransky, Phd

Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Achieving optimal vaccination rates is vital for protecting the health and well-being of all individuals. This specific study focuses on the MMR and RSV vaccines in pregnancy and early childhood, which have been shown to reduce RSV and MMR-related illnesses, hospitalizations, and deaths. Efforts to improve vaccination rates have not …

18 years of age All Phase N/A
A Alison Champagne, MD

Blood Pressure Variability and Ischemic Stroke Outcome

The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: To determine the association of BPV with functional/cognitive outcome after ischemic stroke. To determine a pathophysiologic mechanism of BPV's …

18 years of age All Phase N/A
J Jaclyn LoPiccolo, MD, PhD

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

The purpose of this research study is to learn more about the inherited risk for developing lung cancer.

18 years of age All Phase N/A
D Denise Vasquez

GpCRC Pediatric Gastroparesis Registry 2

The objective of the Pediatric Gastroparesis Registry 2 is to create a national prospective registry of children, adolescents, and young adults with gastroparesis and gastroparesis-like syndrome (symptoms of gastroparesis but normal gastric emptying).

8 - 25 years of age All Phase N/A
D Debbie C Jiang, MD

Cognitive Dysfunction in Chronic and Persistent Immune Thrombocytopenia

Individuals with immune thrombocytopenia (ITP) frequently report difficulties with attention and memory. The main question this study seeks to answer is: Do patients with ITP have evidence of cognitive impairment as detected by a cognitive function test battery? To address this issue, participants will take a cognitive function test and …

18 years of age All Phase N/A
M Michael Cheung

Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck

This study will test the ability of a personalized blood test to determine which head and neck cancer patients will have a recurrence after treatment.

18 years of age All Phase N/A
M Matthew J Frigault, MD

Long-term Follow-up of Subjects Treated With CAR T Cells

This is a single site, non-randomized, open-label, long-term safety and efficacy follow-up study for Phase 1 studies that evaluate the safety and efficacy of CAR T cells: NCT05660369 (DF/HCC 22-175) and NCT06026319 (DF/HCC 23-474).

18 years of age All Phase N/A
E Ethan Litman, MD,MS

Remote Fetal Monitoring in High Risk Pregnancies

Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered. However, an NST is operator-dependent due to the nature of Doppler ultrasound and is primarily performed in a clinic and hospital setting. The ability to conduct a clinically …

18 years of age Female Phase N/A
R Rachel Bernier, MPH

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

Newborns with congenital heart disease (CHD) are at increased risk of developing postpartum and postoperative blood clots after cardiac surgery. The molecular mechanisms that are responsible for the clotting profile predisposing children to blood clots in the early stages of life are currently not well described. The goal of this …

1 - 7 years of age All Phase N/A

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

The purpose of this study is to generate clinical evidence on valve safety and performance in subjects treated by redo Transcatheter Aortic Valve Replacement (TAVR).

18 - 105 years of age All Phase N/A

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