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Needham, Massachusetts Clinical Trials

A listing of Needham, Massachusetts clinical trials actively recruiting patient volunteers.

Found 1,314 clinical trials
C Coordinating Center (Remote Enrollment anywhere in US)

T1D Pregnancy & Me

T1D Pregnancy & Me will partner with pregnant participants living with type 1 diabetes (T1D) in the United States to collect real-world data on management of T1D in pregnancy. This is a remote study where participants can complete online surveys and share device data (continuous glucose monitor (CGM) data and …

18 years of age Female Phase N/A
S Shelley Coughlin

Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials. VIBRANT will use several FDA-cleared wearable biosensors and a non-wearable device to collect symptom data from patients with Rett syndrome for up …

years of age All Phase N/A
D Debra Watson-Smith, RN

Biliary Atresia Research Network Northeast

This is a multi-center retrospective chart review to compile a data repository of the management and outcomes of children with biliary atresia. Overall, investigators aim to evaluate which specific factors contribute to improved patient outcomes, to help guide potential improvements in patient care and resource utilization.

- 12 years of age All Phase N/A
B Brynn Siles, BS

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers. The main questions it aims to answer are: whether children's statistical learning abilities can predict their long-term improvement of language …

72 - 90 years of age All Phase N/A

Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS

The goal of this study is to evaluate if a novel near-infrared spectroscopy (NIRS) device can accurately estimate blood pressure in newborns at risk for unstable blood pressure. The main questions it aims to answer are: Can NIRS accurately estimate blood pressure when compared to the gold standard, arterial line …

24 - 44 years of age All Phase N/A
M Michelle Stransky, Phd

Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Achieving optimal vaccination rates is vital for protecting the health and well-being of all individuals. This specific study focuses on the MMR and RSV vaccines in pregnancy and early childhood, which have been shown to reduce RSV and MMR-related illnesses, hospitalizations, and deaths. Efforts to improve vaccination rates have not …

18 years of age All Phase N/A
M Matthew S Ware, MS

Respiratory Microbiota and Immune Response in CVID

Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency. Respiratory ailments are the most frequent complications of CVID, with chronic pulmonary disease developing in 30-60% and even more experiencing frequent acute respiratory infections. This project aims to establish cutting-edge approaches to study pulmonary biology in CVID and apply …

18 - 80 years of age All Phase N/A
J Jaclyn LoPiccolo, MD, PhD

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

The purpose of this research study is to learn more about the inherited risk for developing lung cancer.

18 years of age All Phase N/A
H Heather Charron

GpCRC Pediatric Gastroparesis Registry 2

The objective of the Pediatric Gastroparesis Registry 2 is to create a national prospective registry of children, adolescents, and young adults with gastroparesis and gastroparesis-like syndrome (symptoms of gastroparesis but normal gastric emptying).

8 - 25 years of age All Phase N/A

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Long-term, multicenter, multinational, observational, registry of patients with AQP4+ NMOSD that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT). The registry will also collect data on patient reported outcomes (PROs), quality of life (QoL), and targeted AQP4+ NMOSD therapies used …

18 years of age All Phase N/A

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