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Natick, Massachusetts Clinical Trials

A listing of Natick, Massachusetts clinical trials actively recruiting patient volunteers.

Found 50 clinical trials
S Sophie Mitchell

Study of Novel Therapeutics for Acute Remedy of Colitis

This study is a clinical trial being done to investigate the efficacy of drug BRS201 as a treatment in patients with acute ulcerative colitis. Patients who qualify are adults who have not responded to treatments for their severe ulcerative colitis. Participation in this study will take 12 weeks long and …

18 - 75 years of age All Phase 2
J Jolin B Yamin, PhD

Brief Intervention for Chronic Pain and History of Stressful Experiences

The goal of this study is to understand whether a brief, three session program can be helpful in reducing symptoms related to both chronic pain and stressful experiences/trauma.

21 years of age All Phase N/A

Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints

This study examines how cochlear implant users understand and comprehend speech in realistic communication situations. Through six experiments measuring listening effort via pupillometry and discourse comprehension, we will investigate how linguistic context, cognitive demands, and processing time affect speech understanding in CI users, and in normal-hearing controls) to identify factors …

18 - 80 years of age All Phase N/A
P Prinicipal Investigator

Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study

This study is designed to evaluate the safety and effectiveness of multiple 1% tolnaftate formulations delivered through novel stick-based vehicles in individuals with tinea pedis (athlete's foot).

16 years of age All Phase 2
S Seneca Ellis

Cognitive Training to Enhance Brain Concordance During Acupuncture

This study will evaluate the impact of a novel non-pharmacological multimodal therapy, a type of approach known to improve pain outcomes and recommended by the Institute of Medicine report for chronic pain management. This study design will also allow the investigators to evaluate a neural model supporting therapeutic alliance for …

18 - 65 years of age All Phase N/A
J Jacqui Guzman, BA

Chronic Non-Specific Neck Pain Treated With Tai Chi and Chiropractic Care

This feasibility project aims to evaluate the effectiveness of chiropractic care combined with Tai Chi (TC) training to reduce pain and disability in adults with chronic non-specific neck pain (CNNP).

18 - 65 years of age All Phase N/A
J Jessica G Labadie, MD

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

The first goal of this clinical trial is to learn if topical application of PLLA in conjunction with a microneedling treatment works to treat perioral wrinkles in adults. The second goal is to see whether the application of topical PLLA is more effective before or after a microneedling treatment. The …

40 - 70 years of age All Phase 4

A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque Psoriasis

The purpose of this study is to understand the comparative effectiveness of deucravacitinib versus apremilast in adults with plaque psoriasis.

18 years of age All Phase N/A
C Cathy Cheney

CorEvitas Generalized Pustular Psoriasis (GPP) Drug Safety and Effectiveness Registry

Prospective, observational registry for subjects with GPP under the care of a dermatology investigator.Approximately 200 subjects and 75 clinical sites in North America will be recruited to participate with no defined upper limit for either target

18 years of age All Phase N/A
S Sara Loud, MS, MSEE

iConquerMS™ - A Patient-Powered Research Network for Multiple Sclerosis

iConquerMS™ is a research initiative developed by and for people with multiple sclerosis (MS) to contribute their health data and ideas to advance and accelerate research into MS.

21 years of age All Phase N/A

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