Milford, Massachusetts Clinical Trials

N Natalie Sinclair, MD

ALPINE: Maintenance Letrozole/Abemaciclib

The purpose of this research study is to see if the study drugs abemaciclib and letrozole are effective and safe for participants with estrogen-receptor positive (ER+), mismatch repair proficient, tumor protein p53 (TP53) wild-type endometrial cancer. The names of the study drugs involved in this study are: Abemaciclib (a type …

P Prinicipal Investigator

Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study

This study is designed to evaluate the safety and effectiveness of multiple 1% tolnaftate formulations delivered through novel stick-based vehicles in individuals with tinea pedis (athlete's foot).

O Oruka Investigative Site

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

This is a multicenter, randomized, double-blinded, placebo-controlled, dose-range finding study to evaluate the efficacy and safety of ORKA-002 in adult participants with moderate-to-severe plaque psoriasis.