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E Watertown, Massachusetts Clinical Trials

A listing of E Watertown, Massachusetts clinical trials actively recruiting patient volunteers.

Found 1,901 clinical trials
M Mingyang Song, MD

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery, chemotherapy and radiotherapy) for stage I-III colorectal cancer.

18 years of age All Phase 1/2
C Camryn Isemann

Confirmation of Diet as a Treatment for Gulf War Illness

This clinical trial aims to confirm previous findings from a smaller study which demonstrated significant improvements in all symptoms among veterans with Gulf War Illness after one month on the dietary intervention. The main objectives of this study are: 1) to confirm previous findings of treatment response to the diet …

50 - 75 years of age All Phase 3
L Lakshmi Nayak, MD

Acalabrutinib in CNSL

This research study is a Phase 1/2 clinical trial testing the safety, tolerance and efficacy of the drug Acalabrutinib for people with recurrent or refractory central nervous system lymphoma (CNSL).

18 years of age All Phase 1/2
M Marcelo Di Carli, MD

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk

The study protocol is a single-arm, open label pilot study designed to evaluate the impact of PCSK-9 inhibition on coronary blood flow in patients with stable coronary artery disease. Patients with stable coronary artery disease will be recruited from the BWH Cardiovascular Medicine clinic and/or from the BWH Nuclear Cardiology …

50 - 90 years of age All Phase 4
B Brad Manor, PhD

Feasibility of Home-based tDCS for Older Adults at Risk of Falling

In this project, the investigators propose to demonstrate the feasibility of remotely-monitored, caregiver (or spouse)-administered, home-based tDCS intervention to improve mobility in ambulatory older adults with recent falls. This is a three-phase feasibility study in older, ambulatory adult participants at risk of falling due to a loss of balance (participant …

60 years of age All Phase N/A
P Panagiotis Konstantinopoulos, MD

Abemaciclib + Letrozole +/- Metformin in Recurrent or Persistent Endometrial Cancer

This research study is studying a combination of targeted therapies as a possible treatment for estrogen-receptor positive (ER+) endometrial cancer. The drugs involved in this study are: Abemaciclib (also known as Verzenio™) Letrozole (also known as Femara®) Metformin (also known as Glucophage®)

18 years of age Female Phase 2
S Sara Bouberhan

Genetic Testing Decision Aid

This is a randomized trial to evaluate the effectiveness of an electronic decision aid tool versus a traditional genetic counselor session for multi-gene panel testing for people with ovarian or pancreatic cancer

18 years of age All Phase N/A
M Milena Braga, MD

Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone

The overall goal of this study is to evaluate the effect of a testosterone drug called Depo-Testosterone (or 'testosterone cypionate'), an FDA-approved drug for improving fatigue, sexual function, quality of life, body composition, muscle strength, and physical activity in young cancer survivors who report fatigue and have low testosterone. Main …

18 - 54 years of age Male Phase 2
A Anna Gao, RN

Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System

The goal of this research is to test a distal scanning capsule and a compact redesigned version of the OFDI imaging system in healthy and BE subjects to assess ease of use, safety and feasibility in preparation for its use in a multicenter clinical trial.

18 - 70 years of age All Phase N/A
T Toshiyuki Nagai, MD

Cardiac Sarcoidosis Randomized Trial

Prospective randomized controlled trial comparing low dose Prednisone(or Prednisolone)/Methotrexate combination to standard dose Prednisone(or Prednisolone) in patients diagnosed with acute active clinically manifest cardiac sarcoidosis and not yet treated. The Investigators hypothesize that low dose Prednisone(or Prednisolone)/Methotrexate combination will be as effective as standard dose Prednisone(or Prednisolone), and result in …

18 years of age All Phase 3

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