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Charlestown, Massachusetts Clinical Trials

A listing of Charlestown, Massachusetts clinical trials actively recruiting patient volunteers.

Found 2,338 clinical trials
J Jessica G Labadie, MD

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

The first goal of this clinical trial is to learn if topical application of PLLA in conjunction with a microneedling treatment works to treat perioral wrinkles in adults. The second goal is to see whether the application of topical PLLA is more effective before or after a microneedling treatment. The …

40 - 70 years of age All Phase 4

Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares

This is a randomized, multicenter, double-blind, single administration study to investigate the efficacy and safety of 2 dosing regimens of Purified Cortrophin® Gel in the treatment of an acute gouty arthritis flare. The study consists of three periods: an optional pre-screening period, a double-blind treatment period, and a 7-day follow-up …

18 - 90 years of age All Phase 4
D Daniel Lee

Modulation Effect of tACS on Chronic Low Back Pain

Investigating the modulation effect of tACS

18 - 60 years of age All Phase 2
S Stephen Tringale Dr. Tringale, MD, MA, FAAFP

CRC Screening in Unscreened Individuals 45-54

The goal of this observational study is to understand the barriers and facilitators to completing colorectal cancer screening from the patient and community health center staff perspective. The main question it aims to answer is to identify system-level determinants of colorectal cancer screening in individuals aged 45 to 54. Participants …

45 - 54 years of age All Phase N/A
A Alexandra J Berger Eberhardt, MD

A Trial of Self-Adjusted Nitrous Versus Placebo During Office Vasectomy

The goal of this clinical trial is to see if nitrous oxide is safe and effective to use during during vasectomies performed in a clinic/in-office setting. This trial will compare self-administered nitrous oxide versus a placebo (oxygen) during office vasectomy. The main questions it aims to answer are: Whether self-administered …

18 - 85 years of age Male Phase 0
A Anna Fratello

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic surgery.

years of age All Phase 2
A Ana-Maria Vranceanu, PhD

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

The purpose of the present investigation is to test the efficacy of a virtual, brief (6 sessions) dyadic (patient and care-partner together) intervention to prevent chronic emotional distress in dyads where one person is diagnosed with Young Onset Dementia (YOD). Through this study, we seek to address the unmet need …

18 - 65 years of age All Phase N/A
A Alessandra Anzolin, PhD

Linked Outcomes in Various EEG-Hyperscanning Setups

The goal of this observational study is to investigate how brains of healthy controls respond when they interact with their romantic partner compared to when they interact with a stranger. The main goals are: Explore how two people's brains interact with each other by recording brain activity at the same …

20 - 60 years of age All Phase N/A
J Jennifer Stamps, PhD

Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

The VR-CARES project is an innovative, collaborative effort that invites dementia care professionals into the design process of a virtual reality platform seeking to mitigate their work-related burden and social isolation by cultivating a virtual community of support. The co-created, caregiver-specific VR platform will serve as a safe, communal space …

18 years of age All Phase N/A
R Rachel Rodgers, PhD

Body Acceptance After Baby Intervention

The purpose of this study is to learn if a novel online single-session intervention can help improve body dissatisfaction in new moms. The active intervention condition, Body Acceptance After Baby (BABI), uses acceptance-based skills to help participants cope with body dissatisfaction. BABI will be evaluated against another active intervention condition …

18 years of age Female Phase N/A

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