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Cambridge, Massachusetts Clinical Trials

A listing of Cambridge, Massachusetts clinical trials actively recruiting patient volunteers.

Found 2,400 clinical trials
J Julia Ivey

The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

To determine safety and effectiveness of the p48 MW HPC and p64 MW HPC Flow Modulation Device in the treatment of wide-necked intracranial aneurysms.

18 years of age All Phase N/A
M Michael Cheung

Electrostimulation Study for Ocular Graft vs. Host Disease

This trial is testing to see if electrostimulation treatment (ET) will be effective in treating those with ocular Graft vs. Host Disease.

18 - 75 years of age All Phase N/A
M Michele B. Ryan, MS

Trans-nasal Endoscopy for Bariatric Patients

This study plans to learn if the EvoEndo Endoscopy system can be used to evaluate, provide and follow up care for upper gastrointestinal tract diseases in the bariatric population. The smallest current scope available for such a technique is an adult transnasal endoscope with a larger diameter, a pulmonary bronchoscope …

18 - 90 years of age All Phase N/A
J John Ohman

Endovascular Repair With Fenestrated TREO Stent-Graft System in AAA

The goal of this clinical trial is to learn if the Fenestrated TREO Stent-Graft System works to treat abdominal aneurysms in adults. An abdominal aneurysm is a bulge in the main blood vessel (the aorta) which carries blood from the heart, through the chest and abdomen. It will also learn …

18 years of age All Phase N/A
B Bradley A McGregor, MD

Sacituzumab Govitecan Plus EV in Metastatic UC

Phase I of this research study will assess what doses of Sacituzumab Govitecan and Enfortumab Vedotin can be safely combined in the treatment of metastatic urothelial carcinoma (mUC). In Phase II of the study, patients in one of the two cohorts will receive Sacituzumab Govitecan, Enfortumab Vedotin, and Pembrolizumab to …

18 years of age All Phase 1/2
M Michael Osborne, MD

Impact of Earplugs on Mechanisms of Noise-Related Cardiovascular Disease

Noise from cars, planes, and trains affects all people and has been associated with heart disease. Almost 30% of Americans are exposed to harmful levels of noise and noise accounts for the loss of more than one million healthy life years per year in Europe. Noise causes stress and may …

18 - 65 years of age All Phase N/A
A Ashley O'Meara

First-in-human Study of 7MW4911 in GI Cancer

This is the first-in-human study of 7MW4911 in US patients, to investigate its prelimary safety and efficacy in patients with gastrointestinal cancers.

18 years of age All Phase 1/2
M Mohammad Amjad

Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

This is an open-label, multicenter, randomized, phase 2 clinical study to evaluate the efficacy of \[177Lu\]Lu-DOTATATE in patients with progressive grade 1-3 intracranial meningioma.

18 years of age All Phase 2
S Sun Kim, PhD, RN

ACT Lung Health Intervention: Phase Two

This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.

18 - 100 years of age All Phase N/A
L Lorenzo Mordini, DDS, MS

Healing Outcomes of Peri-implant Soft Tissues With Different Healing Abutments

The purpose of this study is to compare how well our research participants heal with two different kind of healing abutments used. One is pre-fabricated, meaning it is made to fit anyone, and the other is customized to fit the subject specifically. Much of what will occur is 'standard of …

18 years of age All Phase N/A

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