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Indianapolis, Indiana Clinical Trials

A listing of Indianapolis, Indiana clinical trials actively recruiting patient volunteers.

Found 375 clinical trials
R Rosa Chu

Esprit BTK Post-Approval Study

The Esprit BTK PAS is a prospective, single-arm, multi-center observational study to assess the continued safety and effectiveness of the Esprit™ BTK Everolimus Eluting Resorbable Scaffold System under commercial use, in patients with diseased infrapopliteal lesions causing CLTI (Chronic Limb-Threatening Ischemia) in a real-world setting. The clinical investigation will be …

18 years of age All Phase N/A
D Dawn M Bravata, MD

Pharmacogenomic Informed Statin Prescribing

Statins are the most cost-effective medications to lower cholesterol and cardiovascular disease (CVD) risk. However, many patients at high-risk for CVD do not accept or adhere to statins. This gap in patient's use of statins limits the full impact of these effective medications resulting in higher cholesterol levels and CVD …

40 - 75 years of age All Phase N/A
M Marianne Price, PhD

Plasma Rich in Growth Factors in Corneal Endothelial Transplantation

The purpose of the study is to determine the safety and efficacy of brief intraoperative corneal endothelial graft incubation in plasma rich in growth factors (PRGF) for reducing postoperative endothelial cell loss.

18 - 80 years of age All Phase N/A
P Patient contact

A Study of VET3-TGI in Patients With Solid Tumors

VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study is designed to find a safe and effective dose of VET3-TGI when administered by direct injection into tumor(s) (called an intratumoral injection) or when given intravenously (into …

18 years of age All Phase 1
S Seethal Jacob, MD

Ultrasound Acute Chest Syndrome Sickle Cell Disease

Feasibility and reliability of ultrasound in the inpatient hematology setting.

- 25 years of age All Phase N/A
M Malori Pojar

Exercise as Maintenance Therapy in Advanced Lung Cancer

The purpose of this study is to examine how a multimodality (having or using a variety of methods to do something) exercise intervention may improve survival, function, and quality of life in participants with advanced lung cancer.

18 years of age All Phase N/A
S Shannon Lehman

Study of 68Ga-R10602

A phase 1 imaging study of 68Ga-R10602 in hormone-receptor positive breast cancer.

18 years of age All Phase 1
A Ally Stevens

A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer

A phase 1 study of 68Ga-R11228 and 177Lu-R11228 in breast cancer.

18 years of age All Phase 1
B Barry Barker

Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial

Th Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial. SCIMITAR builds on our pilot study, the Feasibility and Acceptability of Music Imagery and Listening Interventions for Analgesia (FAMILIA), which demonstrated that telehealth delivery of music listening (ML) and music imagery (MI) interventions is feasible and acceptable to …

18 years of age All Phase N/A
B Bryce Hockman

Molecular Mechanisms Associated With Breast Implant Complications

Bacterial biofilms cause implant failures, chronic inflammation, and immune polarization. The study investigates the possible role of bacterial biofilm as a factor in the etiology of Breast Implant Illness. Three patient cohorts will be studied (A) Subjects with breast implant with BII manifestations (B) Subjects with breast implants without BII …

18 years of age Female Phase N/A

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