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Durate, Illinois Clinical Trials

A listing of Durate, Illinois clinical trials actively recruiting patient volunteers.

Found 971 clinical trials
A Angelina Izguerra, BPH

Implementation of Population Breast Cancer Genetic Services in Federally Qualified Health Centers (FQHC)

The goal of this clinical trial is for researchers to compare the effectiveness of a mainstreamed model of genetic testing (MGT) with an enhanced standard of care model (SOC+) on the uptake of genetic testing among at-risk patients in an urban Federally Qualified Health Center (primary care) setting using a …

25 years of age All Phase N/A
S Site Public Contact

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

Breast cancer is not only the leading cause of cancer in women, but also the leading cause of cancer deaths in women. Estrogen receptor-positive and HER2-negative breast cancer is the most prevalent breast cancer subtype. Endocrine therapy is the mainstay of treatment; however, due to the varied nature of the …

18 years of age All Phase 2
S Shraddha Sudhir

Ischemic Preconditioning in Osteoarthritis and Back Pain

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

50 years of age All Phase N/A
M My Le

Enhancing Rehabilitation Participation in Patients With SCI/D Using Motivational Interviewing

The purpose of this multi-site clinical trial is to see whether people with spinal cord injury or disorder (SCI/D) demonstrate higher level of participation in rehabilitation sessions and other outcomes when their therapists are trained in a counseling style called motivational interviewing. We want to answer the following questions: Do …

18 years of age All Phase N/A
S Susan Horner, PhD

Impact of Hospital to Home: Optimizing Preterm Infant Environment for Surgical Neonates and Their Parents (H-HOPE)

Infants born with congenital defects may require major surgery in the neonatal period. These infants are at risk for neurodevelopmental impairments. Additionally, their parents are at higher risk for adverse mental health outcomes. Early relationships are essential to healthy growth and development in all children. Relationships between parents and infants …

1 - 8 years of age All Phase N/A

STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study

This is a non-randomized two-arm trial, specifically a pilot study in which patients with advanced solid tumor cancer with 3-10 metastatic lesions who are on immunotherapy will receive ablative RT to up to 10 lesions. After study intervention, participants will undergo ctDNA collection at 8 weeks after completion of ablative …

18 years of age All Phase 1
S Scott T Youngquist, MD, MS

A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy

This is a multi-site feasibility trial of an embedded emergency department (ED) physical therapy care model for low back pain at two EDs in the Northwestern Medicine and University of Utah Health systems. The study intervention (embedded ED physical therapy) is a reconceptualization of the traditional outpatient physical therapy care …

18 years of age All Phase N/A
B Brent I Rappaport, Ph.D.

Test of Target Engagement of Ambiguity Aversion

The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.

25 - 60 years of age All Phase N/A
J Justin B Hill, B.A.

Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis

In this prospective, open-label, single-arm, single-institution trial, the investigators will accomplish the following two aims: study the safety and tolerability of Ublituximab (Briumvi) twice annually in participants with early MS over a treatment observation period of \~12 months. study the pre- and post-treatment change in plasma neurofilament light chain, tested …

18 - 70 years of age All Phase 4
J Jessica Martinez, BA

Performance Evaluation of Dream OCT: AP Study

This study will evaluate the clinical performance of a new swept-source OCT imaging device, the VG200D, and to evaluate substantial equivalence with a predicate device, the Cirrus 5000. Clinical performance will be assessed through an agreement and precision analysis of OCT measurement parameters.

22 years of age All Phase N/A

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