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Chicago, Illinois Clinical Trials

A listing of Chicago, Illinois clinical trials actively recruiting patient volunteers.

Found 1,108 clinical trials
E Enrico Benedetti, MD

Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device

Approximately 50% of people with multiple sclerosis (MS) use a wheelchair within 30 years of the initial diagnosis. Wheelchair use in MS is often associated with fatigue as a consequence of muscle weakness. Indeed, fatigue, a prevalent consequence of MS, often becomes debilitating and exhausts energetic resources when carrying-out tasks …

18 years of age All Phase N/A
D Devalingam Mahalingam, MD, PhD

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

This phase II trial tests how well pemetrexed works in treating patients with urothelial bladder cancer and other solid tumors that have spread from where they first started (primary site) to other places in the body (metastatic) with mutations that result in a loss of function in the MLL4-protein/KMT2D-gene or …

18 years of age All Phase 2

Point-of-Care Echocardiography in Patients with Known or Suspected Aortic Stenosis

This is a prospective clinical trial intended to capture echocardiographic images in patients clinically indicated for an echocardiographic examination using an additional Point of Care Ultrasound device . The images collected will be used to test and possibly validation an AI base Aortic Valve Stenosis algorithm

18 years of age All Phase N/A

Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures

The primary aim is to assess the impact of laser setting frequency and wattage during holmium laser enucleation of the prostate. There is currently no gold-standard laser settings for HoLEP procedures. In the investigator's current high-volume practice, the following settings for enucleation are: 2j 50hz. These settings are conventional settings, …

18 - 89 years of age Male Phase N/A
J Jinxuan Shi, MS

Reducing Disparities in Urinary Control Symptoms for Minority Women

The study is designed to address the disparity in available conservative/behavioral treatments for UI/LUTS. The program was developed by experts from urogynecology, psychology, and physical therapy then modified based on focus group feedback from racially minoritized women. The study team created a patient-centered, culturally adapted, self-directed, 8-week, home-based module for …

18 years of age Female Phase N/A
E Elizabeth Legorreta, MSN, NP-C

E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control

This study aims to compare a multidisciplinary clinical hypertension and social needs intervention to enhanced standard of care for hypertension management in primary care clinics with regards to hypertension control outcomes.

18 years of age All Phase N/A

Myopia Control: a Comparison Study Between Atropine and MiSight

This research project aims to provide additional knowledge of pharmacological and optical methods of myopia control and to gain a better understanding of the biometry of the pediatric eye, which contributes to the onset and progression of myopia. As a result, this study will improving our best practices for myopia …

5 - 12 years of age All Phase 2
B BOLD-HTN

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

This is a Phase 2 dose-titration study designed to evaluate the safety and efficacy of MANP subcutaneous injection compared to placebo in reducing baseline daytime systolic blood pressure (SBP), derived from 24-hour ambulatory blood pressure monitoring (ABPM), in subjects with hypertension who are taking 3 or more antihypertensive medications with …

18 - 80 years of age All Phase 2
K Katy Magee, M.H.S. SLP

Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation

The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous auricular vagus nerve stimulation (tVNS) to enhance cognitive recovery in patients with mild-moderate traumatic brain injury (TBI).

18 - 65 years of age All Phase N/A
M Mathew M Thambi, PharmD, MPH

Effect of Continuing Versus Holding Metformin During Hospitalizations.

A randomized study of continuing versus holding metformin during hospitalizations to internal medicine services to determine the effects on glucose control, acidosis, abdominal symptoms, length of stay, and mortality.

18 - 110 years of age All Phase 4

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