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Gainesville, Florida Clinical Trials

A listing of Gainesville, Florida clinical trials actively recruiting patient volunteers.

Found 272 clinical trials
E Emily J Fox, DPT,PhD

Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults

Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain stimulation may be effective at restoring lost function. This study tests whether electrical stimulation of prefrontal brain regions is more beneficial than …

65 years of age All Phase N/A
D Dimitrios Kostopolous

Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy

This study will compare two methods of electrical stimulation (alternating current and direct current) as an adjunctive therapy to treating lumbosacral radiculopathy. Both types of electrical stimulation have been used in clinical practice for physical therapy, however direct current stimulation is much less common and there is less known about …

18 years of age All Phase N/A
A Amy Gunnett

Open Label Dose Ranging Study Assessing the Safety of Cord Blood Product in Sacroiliac Joint Syndrome (SIJ)

This is a Phase 1 trial. The overall objective is to evaluate the safety and potential efficacy effect of specific type of umbilical cord blood product (CFL001), which, other than specific modifications in manufacturing to render it compatible with cGMP, is essentially similar to that reported in real-world experience.

18 - 90 years of age All Phase 1
A Aprinda Indahlastari, PhD

Aging Intervention for MCI Population: The AIM Pilot Study

The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy control

60 - 95 years of age All Phase N/A

Study of ATX-01 in Participants With DM1

The goal of this clinical trial is to test ATX-01 in participants with myotonic dystrophy type 1 (DM1). The main question it aims to answer is if ATX-01 is safe and well tolerated. The trial will compare the safety and tolerability of ATX-01 and a matching placebo. There will be …

18 - 64 years of age All Phase 1/2
R Rachel Brown

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab

This study will evaluate the pharmacokinetics, pharmacodynamics, safety and tolerability of a new dosage of ofatumumab compared to the approved dosage of ofatumumab followed by extended treatment in participants with relapsing multiple sclerosis.

18 - 100 years of age All Phase 3
E Erika Barahona, M. Ed

Developing a Scalable Tobacco Cessation Program for Cancer Survivors and Caregivers

Given the challenges to delivering tobacco cessation treatment in oncology care and the unique challenges faced by individuals attempting to quit tobacco after a cancer diagnosis, scalable cessation programs that are tailored to the experiences of cancer survivors that also integrate caregiver/family support are needed. To address this need, this …

18 years of age All Phase N/A

Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease

Locomotor adaptation will be studied using an established split-belt treadmill paradigm, consisting of baseline (1:1 speed ratio), split-belt adaptation (2:1) and post-adaptation (1:1) walking. Split-belt walking will be performed under DBS ON and DBS OFF conditions, while off-medication.

18 - 80 years of age All Phase N/A
S Shea Herlihy, MS

BFRT for Subacromial Pain

The goal of this pilot clinical trial is to learn if blood flow restriction training is safe and feasible in patients with subacromial pain. The main questions the investigators aim to answer are: What problems do participants with shoulder pain encounter when training with blood flow restriction? Is it feasible …

18 - 50 years of age All Phase N/A
M Melissa Makhoul, Phd, MSN, RN

Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain

The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain. The study will also look at whether this activity is helpful in reducing pain and how much it interferes with daily …

18 - 80 years of age All Phase N/A

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