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North Haven, Connecticut Clinical Trials

A listing of North Haven, Connecticut clinical trials actively recruiting patient volunteers.

Found 520 clinical trials
K Kelly Cosgrove, PhD

Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat

The overall objective of this study it to use Positron Emission Tomography (PET) brain imaging and a radiotracer that measures the epigenetic marker Histone Deacetylase 6 (HDAC6) to examine HDAC6 expression in people with Post-Traumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), or concurrent PTSD and AUD with control groups. …

18 - 70 years of age All Phase N/A
A Alison Champagne, MD

Blood Pressure Variability and Ischemic Stroke Outcome

The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: To determine the association of BPV with functional/cognitive outcome after ischemic stroke. To determine a pathophysiologic mechanism of BPV's …

18 years of age All Phase N/A

The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)

Recurrent respiratory papillomatosis (RRP) is an orphan disease that affects approximately 20,000 people in the United States and is caused by infection with human papillomavirus (HPV) types 6 and 11. Since RRP is an orphan disease, it is an understudied disease entity with correspondingly few treatment options. The investigators hypothesize …

18 - 99 years of age All Phase N/A

Psychedelic Virtual Reality

The purpose of this study is to evaluate a novel VRP.

21 - 65 years of age All Phase N/A
R Rachel Dalthorp, MD

The OBSERVE Protocol

This observational protocol is intended to provide long-term follow-up data on patients initiating or continuing treatment with either Spravato® or IV ketamine. This can provide us information on the patient acceptability and satisfaction, patterns of use, long-term effectiveness, and safety of the two approaches. This 5-year, 6-site study will enroll …

years of age All Phase N/A
Z Zhongyao Li

Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.

12 - 18 years of age All Phase N/A

Home-based Oral Glucose Tolerance Test for Type 1 Diabetes Screening

This study aims at quantifying the accuracy of a self-administered fingerstick based glucose tolerance test (GTT@Home) respect to the gold-standard in-clinic venous plasma measures during the oral glucose tolerance test (OGTT) across a wide range of glycemic values in people at risk for clinical type 1 diabetes (T1D) (carriers of …

8 - 45 years of age All Phase N/A
J Jialing Zhang, PhD

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

This is an observational long-term follow-up (LTFU) study for subjects who previously received zamtocabtagene autoleucel, known as MB-CART2019.1.

18 years of age All Phase N/A
J Jemima Duroseau, BSN, RN, MPH

Von Willebrand Factor in Pregnancy (VIP) Study

In pregnant women with von Willebrand disease (VWD) who by the third trimester do not have von Willebrand factor (VWF) or factor VIII (FVIII) levels greater than 50-100%, specific guidance is lacking for delivery planning in terms of how high of a VWF level should be achieved to reduce bleeding. …

18 years of age Female Phase N/A
D Donna McMahon

SPECT/CT Imaging of Skeletal Muscle Perfusion

This study will use SPECT/CT imaging to assess the effect of percutaneous revascularization treatments in patients with Peripheral arterial disease and diabetes mellitus, in whom the disease can progress more quickly than in patients without diabetes.

18 years of age All Phase N/A

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