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Aurora, Colorado Clinical Trials

A listing of Aurora, Colorado clinical trials actively recruiting patient volunteers.

Found 1,071 clinical trials
E Evamaria Kent Bravo, MS

Cirtuvivint/Olaparib in Breast Cancer Susceptibility Gene/Homologous Recombination Deficiency Platinum Resistant Ovarian Cancer

The purpose of this study is to learn about the safety and tolerability of Cirtuvivint in combination with Olaparib in platinum resistant ovarian cancer. The study also aims to determine the recommended dose of the combination therapy. If a participant is a good fit for the study, and they enroll …

18 years of age Female Phase 1
E Edward Melanson, Ph.D.

Thermogenenic Responses to Fasting and Overfeeding in Women

This study plans to learn more about why menopause increases the risk of weight gain. During and after menopause, women are prone to increased weight gain. The weight gained is primarily body fat, particularly visceral or abdominal body fat. The excess gain in abdominal fat during menopause increases the risk …

18 - 65 years of age Female Phase N/A

A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

The goal of this clinical trial is to investigate if treatment with bulumtatug fuvedotin is effective in triple-negative breast cancer patients who have previously received treatment with an antibody-drug conjugates.

18 years of age All Phase 1

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

This is a phase 2b open-label trial to characterize histopathological biomarkers of disease in immunoglobulin A nephropathy (IgAN) and demonstrate potential changes in response to sibeprenlimab.

16 years of age All Phase 2
C Claudia Musat

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

This is a double-blind, randomized, placebo-controlled, sequential cohort, ascending dose clinical trial to evaluate the safety and determine the efficacy of ascending doses of DB-3Q for the treatment of Perianal Fistulizing Crohn's Disease.

18 - 75 years of age All Phase 2
E Erica Morse, MA

Collaborative Care for Treatment of Depression and Anxiety

The goal of this project is to evaluate the effectiveness of a collaborative care model for primary care patients at Kaiser Permanente Colorado (KPCO) with depression and/or anxiety. Collaborative care uses evidence-based short-term treatments delivered to patients over the phone. We will explore the use of cost-efficient automated processes for …

18 years of age All Phase N/A
J Jared Scorsone

Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors

This study investigates the efficacy of a telehealth exercise program designed specifically for rural cancer survivors with cancer-related fatigue (CRF). Small dried blood samples and measures of physical function will be collected throughout the program. The main questions it aims to answer are: Does the exercise program improve CRF in …

18 - 89 years of age All Phase 2
P Pamela Gerecht, PhD

Adaptive DBS to Offset STN Dysregulation During Exercise in PD

The investigators conduct a prospective study to evaluate the effects of exercise on Parkinson's Disease brain biomarkers detected with the PerceptTM PC neurostimulator.

20 - 70 years of age All Phase N/A
N Noah Lechtzin

Remote Sputum Collection in Cystic Fibrosis

Elexacaftor/Tezacaftor/Ivacaftor or Trikafta improves lung health in people with cystic fibrosis (CF), including decreased cough and mucous production. Diagnosing lung infections has become more challenging due to the decrease in sputum and rise of telehealth services. While the option of collecting sputum samples at home and sending them by mail …

18 years of age All Phase N/A
R Research Service Professional

Innovations in Hearing Accessibility and Technology (IHAT) Study

The research will explore outcomes of different service delivery models of over-the-counter (OTC) hearing aids by comparing them to prescription hearing aids fitted by specialists in individuals with mild to moderate hearing loss. The investigators will examine how each type affects users' experiences, behavior, thinking skills, and brain activity related …

40 years of age All Phase N/A

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