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Tarzana, California Clinical Trials

A listing of Tarzana, California clinical trials actively recruiting patient volunteers.

Found 542 clinical trials
R Ryan Apfel

Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis

An observational study to determine if individuals with increased platelet FcyRIIa will have a higher risk of ischemic events.

30 years of age All Phase N/A

Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression

Despite the prevalence and significant public health concern over depression among adolescents, up to 40% of depressed adolescents do not respond to first-line antidepressants (herein termed treatment non-response, TNR). The goal of this project is to recruit and assess 160 treatment-seeking depressed adolescents and test whether acute stress impacts peripheral …

14 - 21 years of age All Phase N/A
J Jodie Howell

DMCRN-02-001: Assessing Pediatric Endpoints in DM1

The overall goal of the study is to establish valid clinical endpoint assessments for children with congenital myotonic dystrophy type 1 and childhood myotonic dystrophy type 1, and develop biomarkers for the condition.

- 59 years of age All Phase N/A

HIFU for Focal Ablation of Prostate Tissue: An Observational Study

The Sonablate HIFU device was approved by the U.S.FDA for prostate tissue ablation in October, 2015. The purpose of this observational research study is to investigate the localized treatment of prostate cancer using HIFU through clinical data and health-related quality of life (HRQOL) questionnaires.

40 - 85 years of age Male Phase N/A
N Nashla Barroso

Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification

This study evaluates how new magnetic resonance imaging (MRI) and artificial intelligence techniques improve the image quality and quantitative information for future prostate MRI exams in patients with suspicious of confirmed prostate cancer. The MRI and artificial intelligence techniques developed in this study may improve the accuracy in diagnosing prostate …

18 years of age Male Phase N/A
S Site Public Contact

Mechanisms of Resistance to PSMA Radioligand Therapy

This is a multicenter, correlative study to existing Lutetium based prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) trials and uses.

18 years of age All Phase N/A
R Robin Libove, BS

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular biomarkers specific to PTEN ASD. In addition, this study will be creating and maintaining a biorepository and linked …

18 years of age All Phase N/A
S Stefanie Howell, PhD

Traumatic Brain Injury and Stroke Long Term Outcome

Investigators will determine the long-lasting effects of post-acute rehabilitation after traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects of rehabilitation continue after discharge from a rehabilitative program.

18 years of age All Phase N/A
S Site Public Contact

Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms

This is a prospective observational multi-center pilot study of germline testing for participants receiving care at University of California participating locations with a new or existing diagnosis of Pancreatic Neuroendocrine Neoplasms (PanNEN). This protocol is an extension of existing Genetic Testing Station efforts at University of California, San Francisco (UCSF)

18 years of age All Phase N/A
M Megan C Ichinose, PhD

Children's Bipolar Network Treatment Trial I

This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN). CBN sites have expertise in diagnosing, assessing, and treating BSDs in youth. The primary aims of this study are to (1) identify and reliably diagnose …

9 - 19 years of age All Phase N/A

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