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Spring Valley, California Clinical Trials

A listing of Spring Valley, California clinical trials actively recruiting patient volunteers.

Found 441 clinical trials

Randomized Controlled Trial Comparing Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

Ankle fractures are a common injury with potentially significant morbidity. Syndesmosis injury occurs in 10% to 13% of ankle fractures and poses a greater risk to long-term outcomes for patients. The gold standard for syndesmosis fixation has traditionally been screw fixation. However, issues with screw fixation include screw breakage, screw …

18 years of age All Phase N/A
M Melanie Arnold

Strategy for Improving Stroke Treatment Response

SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal antibody against the alpha-2 antiplasmin (a2-AP), in acute ischemic stroke.

18 years of age All Phase 2
M Marisa Sklar, PhD

TEAMS R34 #1 After-Action Reviews in Child Welfare Services

This project proposes to improve successful mental health service linkage in Child Welfare Services (CWS) by adapting and testing the After Action Review (AAR) team effectiveness intervention to augment the Child Family Team (CFT) services intervention. Despite being both required and a collaborative approach to service planning, CFT meetings are …

6 years of age All Phase N/A
B Brian Green, PhD

A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability

The ROCKY REHAB trial will provide a pragmatic approach to evaluate if incorporating a rocky, uneven terrain treadmill into the proprioceptive rehabilitation received during physical therapy can improve outcomes and reduce reinjury rates in patients with ankle instability.

18 - 49 years of age All Phase N/A
E Eva Morava-Kozicz, MD, PhD

Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.

years of age All Phase N/A
S Shanmugasundaram Natesan, PhD

Evaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain

The overall goal of this multisite, randomized clinical trial is to evaluate the short- and long-term effectiveness of a Clinical Practice Guideline (CPG)-adherent physical therapy approach to patellofemoral pain (PFP) management among military Service members. The main questions it aims to answer are: Can a CPG-adherent care approach to PFP …

18 years of age All Phase N/A
S Scott Bainbridge, MD

Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

A Randomized, Double-Blind, Placebo-Controlled, Single Dose Study to Assess the Safety and Efficacy of SL1002 for the Treatment of Knee Pain in Patients with Osteoarthritis of the Knee.

40 years of age All Phase 3
A ASCEND-IBD Trial Center

A First-in-Human Single and Multiple Ascending Dose Study of MT-201

First-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple doses of MT-201 in healthy participants.

19 - 55 years of age All Phase 1
A ASCEND-IBD Trial Center

A First-in-Human Single and Multiple Ascending Dose Study of MT-701

First-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple doses of MT-701 in healthy participants.

19 - 55 years of age All Phase 1
A ASCEND-IBD Trial Center

A First-in-Human Single and Multiple Ascending Dose Study of MT-251

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Doses of MT-251 in Healthy Participants

19 - 55 years of age All Phase 1

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