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Los Angeles, California Clinical Trials

A listing of Los Angeles, California clinical trials actively recruiting patient volunteers.

Found 1,318 clinical trials

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

This is a Phase 2, open-label, single-arm, multicenter study to assess the antimyeloma activity and further characterize the safety, tolerability, PK, and PD of cemsidomide in combination with dexamethasone in participants with relapsed/refractory multiple myeloma (r/r MM).

18 years of age All Phase 2

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

This is a prospective, multicenter, randomized, evaluator-blinded, parallel-controlled, non-inferiority clinical study designed to evaluate the safety and effectiveness of the ULTRAFORMER MPT PLUS, a high-intensity focused ultrasound (HIFU) device, for lifting and tightening lax submental (beneath the chin) and neck tissue in adult subjects. Approximately 273 subjects will be enrolled …

30 - 65 years of age All Phase N/A
J Janet Choi, MD, MPH

New Approach to Objectively Measure Social Engagement in Older Adults With Hearing Loss

The goal of this clinical trial is to learn if hearing devices, like hearing aids, affect social and cognitive function of older adults. The main questions the researchers want to answer are: How social are older adults with hearing loss before and after using hearing devices? How well do older …

60 years of age All Phase N/A
D Denise Tran

An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults

The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility over an 8-week period compared to receiving the control condition in young adults who currently use e-cigarettes. Participants …

18 - 24 years of age All Phase N/A
A Angela Zhu

Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

The goal of this pilot hybrid type I efficacy/implementation trial is to assess a newly developed decision support tool patients, parents, and providers to use during surgical treatment decision making for neuromuscular scoliosis (NMS). Results from this pilot will inform the design of a future larger effectiveness trial of the …

8 years of age All Phase N/A
C Chanita Hughes Halbert, PhD

Data-Driven Strategies for Patient Engagement About Cancer Clinical Trials

This study assesses patient awareness and understanding of cancer clinical trials.

21 years of age All Phase N/A

Continuous Glucose Monitoring (CGM) in Prediabetes With Community Based Recruitment

The objective of this project is to develop a behavioral intervention that combines wearable continuous glucose monitoring (CGM) with smartphone feedback and educational video clips generated by artificial intelligence (AI) software to improve glycemic control among individuals with pre-diabetes. The goal is to prevent transition to type 2 diabetes (T2D).

35 years of age All Phase N/A
H Helen Lavretsky, MD, MS

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Osteoarthritis (OA) is a major public health problem, and involvement of the knee is especially disabling. Symptomatic knee OA has an incidence rate between 40 to 1,020 per 100,000 person years1 and is among the most common causes of disability worldwide. Knee arthritis pain and disability are highly comorbid wiht …

50 - 95 years of age All Phase 0
J Jeffrey I Gold, PhD

Virtual Reality (VR) for Interventional Radiology (IR) Procedures

The goal of this clinical trial is to to utilize Virtual Reality during their interventional radiology procedure to help reduce any pain and anxiety experienced during the procedure in patients above the age of 8 undergoing interventional radiology procedures. The main questions it aims to answer are: To determine if …

8 years of age All Phase N/A
F Fayz Hudefi, MD

Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

This is a Phase 3, randomized, double blind, placebo controlled, fixed dose, study designed to evaluate the efficacy, safety, tolerability, and of LB-102 versus placebo for the treatment of adult patients with an acute exacerbation of schizophrenia.

18 - 65 years of age All Phase 3

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