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Homewood, Alabama Clinical Trials

A listing of Homewood, Alabama clinical trials actively recruiting patient volunteers.

Found 514 clinical trials
R Ralee' Bunt, MSPH

Bodewell Products for the Treatment of Atopic Dermatitis

This study aims to examine the safety and efficacy of topical application of the Bodewell eczema products

18 - 99 years of age All Phase 4
R Ramsha Akhund, MD

Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation

The aim of this study is to determine if fluorescence with or without indocyanine green can facilitate safe and accurate thyroid and parathyroid surgery.

19 years of age All Phase 4

Phase 2 Trial of HY209gel in Atopic Dermatitis Patients

This is a randomized, double-blind, placebo-controlled, multi-center, phase 2 study in patients with mild to moderate Atopic Dermatitis(AD), which consists of 2 parts.

18 - 100 years of age All Phase 2
S Site Public Contact

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

This phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in addition to standard of care chemotherapy versus standard of care chemotherapy alone in treating patients with colorectal cancer that has spread to the liver (liver metastases) and cannot be removed by surgery (unresectable). HAI uses a catheter to …

18 years of age All Phase 3
M Mehmet Akce, MD

ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)

This is an open-label Phase I/Ib dose-escalation, dose-expansion clinical trial of the safety, pharmacokinetics and clinical activity of ProAgio combined with gemcitabine and nab paclitaxel (G-nP) in previously untreated subjects with metastatic pancreatic ductal adenocarcinoma (PDAC)

18 years of age All Phase 1
M MacKenzie Dunlap

Study in Parkinson Disease of Exercise

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

40 - 80 years of age All Phase N/A
C Carol Lin, MD

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

Patients are in 2 cohorts: Cohort 1: dexamethasone, methotrexate, ifosfamide, pegaspargase, and etoposide (modified SMILE) chemotherapy regimen alone and pembrolizumab in children, adolescents, and young adults with advanced stage NK lymphoma and leukemia Cohort 2: combining pralatrexate (PRX) (Cycles 1, 2, 4, 6) and brentuximab vedotin (BV) (Cycles 3, 5) …

1 - 31 years of age All Phase N/A
T Thiru Pillay, BSN

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma

The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma is newly diagnosed, and to evaluate safety and tolerability of this combination at that dose.

18 years of age All Phase 1
L Louis J Dellitalia, MD

Allopurinol Improves Heart Function in African Americans With Resistant Hypertension

African American adults in the United States have the highest prevalence rate of high blood pressure (hypertension) and heart failure in the world. African Americans with treatment resistant hypertension have higher levels of the enzyme - xanthine oxidase compared to Caucasians. This trial will test if administration of the xanthine …

18 - 75 years of age All Phase 2
C Chris Gonzalez

Stimulus-Evoked Directional Field Potentials to Guide Subthalamic and Pallidal DBS for PD

The purpose of the study is to determine whether new deep brain stimulation (DBS) device technologies can generate and record brain rhythms to reveal the best location for clinical stimulation.

18 years of age All Phase N/A

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