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Ealing, United Kingdom Clinical Trials

A listing of Ealing, United Kingdom clinical trials actively recruiting patients volunteers.

Found 1,047 clinical trials
C Chloe L Thackray, BSc

The Growing Well Study

What are the study aims? To understand more about eating habits and age-appropriate food/drink portion sizes of children aged 6 months-5 years old, and how this affects their growth and dental health. Why is this research important? Healthy diets in early years are important for growth and development. However, clear …

6 - 4 years of age All Phase N/A

A Study to Evaluate ALN-4285 in Adult Healthy Volunteers

The purpose of this study is to: evaluate the safety and tolerability of single ascending doses of ALN-4285 in healthy volunteers characterize the single-dose pharmacokinetics (PK) of ALN-4285

18 - 65 years of age All Phase 1
S Study Director

Study of TGM-312-SC01 in Healthy Participants and Adults With MASH

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) effects of single ascending doses of TGM-312-SC01 in healthy adults and multiple ascending doses in patients with metabolic dysfunction-associated steatohepatitis (MASH).

18 - 70 years of age All Phase 1/2

IIH Intervention: A Clinical Trial Comparing 2 Treatments (Shunts and Stents) Evaluation Of Clinical Effectiveness And Cost Effectiveness

Background and study aims Idiopathic intracranial hypertension (IIH) is a neurological condition characterised by increased pressure inside the skull, called intracranial pressure (ICP). It is more common in women of reproductive age with obesity. Common symptoms of IIH include headaches, blurred vision and ringing in the ears. If left untreated, …

18 - 63 years of age All Phase N/A

Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers

This is a multi-centre, randomised, non-inferiority, phase III study in patients with low risk differentiated thyroid cancer. Patients will be identified via oncology multidisciplinary team meetings. There will be two sources of patients in the trial, with the same histological diagnoses and prognosis (i.e. recurrence risk): Group 1: Patients who …

16 years of age All Phase N/A
A Anupam Chakrapani, Dr

Halting Ornithine Transcarbamylase Deficiency With Recombinant AAV in ChildrEn

Ornithine transcarbamylase deficiency (OTCD) is an inherited metabolic liver disease which means that the body cannot maintain normal levels of ammonia. Ammonia levels can rise (called hyperammonaemic decompensations) which can be life-threatening and may result in impaired neurological development in children. OTCD is a rare genetic disorder characterised by complete …

- 16 years of age All Phase 1/2
D Dilruba Kabir

Understanding immunE-related toXicities by multifACeT Profiling

A prospective observational cohort study of patients undergoing CPI therapy in which translational research is the fundamental aspect of the study.

18 years of age All Phase N/A
G George RF Murphy, MA

Muscle Connective Tissue in Limb Development and Disease

The objective of this work is to understand how the disruption of the muscle connective tissue contributes to the limb soft-tissue defects in radial dysplasia. In parallel, the researchers will investigate the role of muscle connective tissue in normal limb development.

years of age All Phase N/A

Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System

The rationale for the study is to obtain safety and efficacy data as well as to establish dose parameters for the SpectraCure P18 System with IDOSE®, with verteporfin for injection (VFI) as photosensitizer for the treatment of recurrent prostate cancer.

18 years of age Male Phase 1/2
R Rajeshwar Mookerjee

CirrhoCare- Using Smart-phone Technology to Enhance Care and Access to Treatment for Cirrhosis

The CirrhoCare trial is a multi-centre, open label randomised controlled trial in patients with decompensated cirrhosis. The trial aims to investigate the clinical and cost-effectiveness of CirrhoCare digital home monitoring and management with current standard of care in these patients.

18 years of age All Phase N/A

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