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Ealing, United Kingdom Clinical Trials

A listing of Ealing, United Kingdom clinical trials actively recruiting patients volunteers.

Found 750 clinical trials
C Christina Caldwell, LPN

A Study of NX-1607 in Adults With Advanced Malignancies

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-1607 in patients with advanced malignancies.

18 years of age All Phase 1
T Tony Goldstone, MRCP PhD

Gut Hormone LEAP2 in Metabolism and Eating Behaviour: Fixed Meal Testing

The goal of this interventional study is to measure the blood levels of the gut hormones LEAP2 and acyl ghrelin (AG), appetite and food intake after consuming liquid meals of different caloric sizes, in healthy adults with and without obesity. AG is a stomach-derived homone that increases appetite, and LEAP2 …

18 - 60 years of age All Phase N/A
L Leah McCauley, MSc

NHS Staff Digital Wellbeing Via AirEmail

The goal of this "digital health intervention" study is to test a novel email management tool called "AirEmail" (version 1, or v1) for its impact on improving key aspects of healthcare email management. The main questions it aims to answer are: What are the effects of technostress in staff employed …

18 years of age All Phase N/A

[18F]FPIA PET/CT Imaging in Patients With Solid Tumours

The study will be a phase 2, open-label study in patients with solid tumours to explore the relationship between short-chain fatty acid uptake using [18F]FPIA PET/CT and tumour proliferation

18 years of age All Phase 2
S Sia Daneshmand

International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

This is an international phase III trial, with a Bayesian design, incorporating two sequential randomisations. It efficiently examines a series of questions that routinely arise in the sequencing of treatment. The study design has evolved from lengthy international consultation that has enabled us to build consensus over which questions arise …

18 years of age Male Phase 3
C Clare Schilling

Lymphatic Mapping Of Oropharyngeal Cancer

A multi-centre validation study to evaluate whether a new imaging and surgical protocol would work as well as the current god standard in identifying sentinel nodes in patients with oropharyngeal cancer.

18 years of age All Phase N/A
R Rosie Jacobs

Hybrid AbLaTion of Atrial Fibrillation

A randomised controlled trial to assess the efficacy of staged hybrid ablation when compared with standard catheter ablation in patients with non-paroxysmal atrial fibrillation (AF)

18 years of age All Phase N/A
A Alison Musson

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

This clinical study is aiming to determine the safest doses and schedule for the combination of two drugs named palbociclib and avelumab. The study will also be investigating how effective the combination is for a subgroup of breast cancer patients whose cancer expresses the androgen receptor (AR) but not the …

18 years of age All Phase 1
L Lucy Campbell

HPV Self-testing in Transgender Individuals

Human papillomavirus (HPV) is a common virus that spreads through skin-to-skin contact. Some HPV types can cause changes in cells that lead to cancer and are known as 'high-risk' HPV (hrHPV). hrHPV is linked to cancers of the cervix (opening of the womb), throat, and anus (exit of the bowel). …

21 - 65 years of age All Phase N/A
D Desire Onwochei, MBBS

Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?

Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak. The key aims when choosing which type of anaesthetic are safety …

18 years of age Female Phase 4

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